ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Threonine derivatives 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid

2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid

2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Basic information
Product Name:2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
Synonyms:FMOC-L-THREONINE extrapure;N-(9-Fluorenylmethoxycarbonyl)-L-threonine ,99%;N-alpha-(9-fluorenylmethyloxycarbonylamino)-3-hydroxybutanoic acid;Fmoc-L-threonine ,99%;Fmoc-L-Threonine monohydrate ,99%;Fmoc-Threonine-OH;2-(9H-Fluoren-9-ylMethoxycarbony-laMino)-3-;FMoc-Thr-OH·H2O FMoc-L-threonine Monohydrate
CAS:73731-37-0
MF:C19H19NO5
MW:341.36
EINECS:1533716-785-6
Product Categories:Amino Acid Derivatives;Amino Acids;Threonine [Thr, T];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series
Mol File:73731-37-0.mol
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Structure
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Chemical Properties
Melting point 115°C (dec.)
alpha -16 º (c=1%, DMF)
Boiling point 596.5±50.0 °C(Predicted)
density 1.327±0.06 g/cm3(Predicted)
refractive index -15.5 ° (C=1, DMF)
storage temp. 2-8°C
solubility soluble in Methanol
form powder to crystal
pka3.49±0.10(Predicted)
color White to Almost white
optical activity[α]20/D 16±1°, c = 1% in DMF
BRN 4300093
CAS DataBase Reference73731-37-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-26
WGK Germany 3
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Usage And Synthesis
Chemical PropertiesWhite powder
UsesN-Fmoc-L-threonine is an N-Fmoc-protected form of L-Threonine (T405500). L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin).
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Preparation Products And Raw materials
Raw materialsmethyl (2S,3R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxybutanoate-->FMOC-O-tert-Butyl-L-threonine-->FMOC-D-THR-OH-->N-Fmoc-L-threonol-->L-Threonine
Preparation ProductsPalmitoyl Pentapeptide-->MELITTIN-->(2S,3S)-FMoc-Abu(3-N3)-OH
FMOC-L-THR(ME)-OH Fmoc-THr(Bzl)-OH FMOC-L-THR(ALPHA-D-MANAC4)-OH FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH FMOC-THR(PO3ME2)-OH FMOC-L-THR(TBU)-O-CH2-PHI-OCH2-CH2-COOH FMOC-THR(PO3H2)-OH FMOC-THR(TBU)-OPFP Fmoc-O-trityl-L-threonine Fmoc-O-tert·butyl-L-threonineN-carboxyanhydride FMOC-THR(AC)-OH Fmoc-O-(benzylphospho)-L-threonine FMOC-O-tert-Butyl-L-threonine TETRA-O-ACETYL-ALPHA-D-GAL-FMOC-THR N-Fmoc-N-Methyl-O-tert-butyl-L-threonine FMOC-L-THR(GAL(1->3)GALNAC)-OH HEPTA-O-ACETYL-BETA-D-LACTOSYL-FMOC-THR 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
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