acepromazine

acepromazine Basic information

Product Name:	acepromazine
Synonyms:	10-(3-DIMETHYLAMINOPROPYL)PHENOTHIAZINE-3-ETHYLONE;Acepromazine (base and/or unspecified salts);1-[10-(3-dimethylaminopropyl)phenothiazin-2-yl]ethanone;1522CB;Acetopromazine;Vetranquil;3598-37-6 (Maleate);A 23051
CAS:	61-00-7
MF:	C19H22N2OS
MW:	326.46
EINECS:	200-496-0
Product Categories:
Mol File:	61-00-7.mol

acepromazine Chemical Properties

Melting point	<25 °C
Boiling point	bp0.5 220-240°
density	1.1075 (rough estimate)
refractive index	1.5950 (estimate)
pka	9.41±0.28(Predicted)
color	Orange oil
Water Solubility	16mg/L(25 ºC)

Safety Information

Toxicity

LD50 intraperitoneal in mouse: 350mg/kg

MSDS Information

acepromazine Usage And Synthesis

Uses	Sedative (veterinary).
Definition	ChEBI: Acepromazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. It has a role as a phenothiazine antipsychotic drug. It is a methyl ketone, an aromatic ketone, a tertiary amino compound and a member of phenothiazines.
Safety Profile	Poison by ingestion, intravenous, and subcutaneous routes. A flammable liquid. When heated to decomposition it emits toxic fumes of SO, and NOx,. See also KETONES. An animal tranquilizer.

acepromazine Preparation Products And Raw materials

Raw materials

1-(2-acetylphenothiazin-10-yl)ethanone-->1-[10-(3-chloropropyl)-10H-phenothiazin-2-yl]ethan-1-one-->methyl phenothiazin-10-yl ketone-->Dimethylamine-->3-Chloro-1-(N,N-dimethyl)propylamine-->2-Acetylphenothiazine-->2-BROMOTHIOPHENOL-->Phenothiazine

1-Propanone, 1-(10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazin-2-yl )-, dimaleate PROPIONYLPROMAZINE HYDROCHLORIDE carfenazine ACEPROMAZINE MALEATE Promazine acepromazine PIPERACETAZINE (250 MG) ACETOPHENAZINE butaperazine

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