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Decloxizine

Decloxizine Basic information
Product Name:Decloxizine
Synonyms:decloxizine;DECLOXIZIN HYDROCHLORIDE;Decloxizine Base;decloxazine;1-benzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine;UCB-1402;NSC-289116;2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol;UCB 1402
CAS:3733-63-9
MF:C21H28N2O2
MW:340.46
EINECS:
Product Categories:Pharmaceutical Intermediates
Mol File:3733-63-9.mol
Decloxizine Structure
Decloxizine Chemical Properties
Boiling point 476.25°C (rough estimate)
density 1.1027 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka14.41±0.10(Predicted)
color Light Beige to Beige
CAS DataBase Reference3733-63-9(CAS DataBase Reference)
Safety Information
ToxicityLD50 orl-rat: 840 mg/kg ARZNAD 18,1002,68
MSDS Information
Decloxizine Usage And Synthesis
UsesDecloxizine is a histamine 1 receptor antagonist. Hydroxyzine (H996500) impurity.
Safety ProfilePoison by intraperitoneal andintravenous routes. Moderately toxic by ingestion. Anexperimental teratogen. Other experimental reproductiveeffects. When heated to decomposition it emits toxicfumes of NOx.
Decloxizine Preparation Products And Raw materials
p-(2-Methoxyethyl) phenol N-Aminoethylpiperazine Ethanol Hydroxyzine METHYL ETHYLCELLULOSE Methyl 2-hydroxyethyl cellulose 1-Methylpiperazine Ethylbenzene 2-Butanone Ethylparaben CHLOROETHANE Piperazine Ethyl cellulose Diethyl ether Ethyl acetate Ethyl acrylate Decloxizin HCL CP2000 Ethoxymethylenemalononitrile
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