| | Isobutyryl chloride Basic information |
| | Isobutyryl chloride Chemical Properties |
| Melting point | -90 °C (lit.) | | Boiling point | 91-93 °C (lit.) | | density | 1.017 g/mL at 25 °C (lit.) | | vapor pressure | 0.07 mm Hg ( 20 °C) | | refractive index | n20/D 1.407(lit.) | | Fp | 34 °F | | storage temp. | Store below +30°C. | | solubility | Miscible with chloroform, glacial acetic acid, ether, toluene, methylene chloride and benzene. | | form | Liquid | | color | Clear | | Odor | Stench | | PH | <7 (H2O) | | explosive limit | 2.1-8.2%(V) | | Water Solubility | Reacts | | Sensitive | Moisture Sensitive | | BRN | 605393 | | CAS DataBase Reference | 79-30-1(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Methylpropanoyl chloride(79-30-1) | | EPA Substance Registry System | Propanoyl chloride, 2-methyl- (79-30-1) |
| Hazard Codes | F,C,T | | Risk Statements | 11-35-23 | | Safety Statements | 16-23-26-36-45-36/37/39-28A | | RIDADR | UN 2395 3/PG 2 | | WGK Germany | 1 | | RTECS | UC3944000 | | F | 13 | | Autoignition Temperature | 325 °C | | Hazard Note | Highly Flammable/Corrosive/Moisture Sensitive | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | II | | HS Code | 29147090 | | HS Code | 29159080 |
| | Isobutyryl chloride Usage And Synthesis |
| Chemical Properties | Colorless liquid.Soluble in ether;
reacts with water and alcohol. | | Uses | Usually used in the synthesis of fully isobutyramide terminated hyperbranched polyethylenimines,the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum. | | Uses | Isobutyryl chloride is used in the preparation of fully isobutyramide terminated hyperbranched polyethylenimines. It plays an important role in the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum L. It acts as an acylating agent for the ketimine derivatives of alfa-amino esters, nucleosides and pyrroles. Further, it is used in the preparation of organic peroxides. In addition to this, it is used as an intermediate for dyes, textile auxiliaries and peroxide compounds. | | General Description | A colorless liquid. Flash point near 50°F. Irritates skin, eyes and mucous membranes. Toxic by ingestion, inhalation and skin absorption. Used to make other chemicals. | | Air & Water Reactions | Highly flammable. Produces corrosive toxic fumes containing HCl on contact with moist air. Decomposes in water. | | Reactivity Profile | Isobutyryl chloride is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. | | Hazard | Low toxicity by inhalation. A severe eye
irritant. | | Health Hazard | May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. | | Fire Hazard | Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. | | Flammability and Explosibility | Highlyflammable |
| | Isobutyryl chloride Preparation Products And Raw materials |
| Raw materials | Sulfur dioxide-->Isobutyric acid-->Methacrylic acid-->Thioacetic acid-->1-(4,5-dihydrooxazol-2-yl)acetone-->2-METHYL-2-OXAZOLINE-->Isobutyric acid hydrazide-->1,3,5-TRIMETHYL-2-(TRICHLOROMETHYL)BENZENE-->2,4,6-Trimethylbenzoyl chloride-->Dichloromethane-->Isobutyraldehyde | | Preparation Products | 2,2-DIMETHYL-3-(2-METHYLPROP-1-ENYL)CYCLOPROPANECARBOXYLIC ACID-->1-Chloro-N,N,2-trimethylpropenylamine-->Etofenprox-->BUCILLAMINE-->Flutamide-->Isobutyramide-->D-(S)-3-acetylthio-2-methylpropionylL-proline-->ISOBUTYRIC ACID ISOPROPYL ESTER-->Isobutyrophenone-->3'-Trifluoromethylisobutyranilide-->Propanoic acid, 2-methyl-2-[[(trimethylsilyl)oxy]sulfonyl]-, trimethylsilyl ester-->PRENYL ISOBUTYRATE |
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