Gallic acid monohydrate

Gallic acid monohydrate Basic information
Product Name:Gallic acid monohydrate
Synonyms:Gallic Acid, Monohydrate, Crystal, Reagent, ACS;Gallic acid monohydrate >=99% (HPLC);Gallic acid monohydrate ACS reagent, >=98.0%;Gallic acid monohydrate Vetec(TM) reagent grade, 98%;Benzoic acid,3,4,5-trihydroxy-, hydrate (1:1);GALLIC ACID-1-HYDRATE;GALLIC ACID MONOHYDRATE;GALLIC ACID, HYDRATE
CAS:5995-86-8
MF:C7H8O6
MW:188.13
EINECS:611-919-7
Product Categories:Pharmaceutical Intermediates;Antioxidant;Biochemistry;ACS Grade;Building Blocks;C7;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;Research Essentials;Solutions and Reagents;Myrica cerifera;Acacia;Aspalathus linearis (Rooibos tea);Cimicifuga racemosa;Ephedra sinica;Euphorbia sp;Nutrition Research;Phytochemicals by Plant (Food/Spice/Herb);s wort);Vaccinium myrtillus (Bilberry)
Mol File:5995-86-8.mol
Gallic acid monohydrate Structure
Gallic acid monohydrate Chemical Properties
Melting point 252 °C (dec.)(lit.)
density 1.694
Fp 250 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility It is soluble in alcohol, ether, glycerol, acetone negligible in benzene, chloroform, petroleum ether.
form Solid
color White to cream
Water Solubility 15 g/l (20 ºC)
Sensitive Hygroscopic
Merck 14,4345
BRN 2050274
Stability:Light Sensitive
InChIKeyIUTKPPDDLYYMBE-UHFFFAOYSA-N
CAS DataBase Reference5995-86-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 2
RTECS LW7525000
8-9-23
TSCA Yes
HS Code 29182900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Gallic acid monohydrate Usage And Synthesis
Chemical PropertiesOff-white to beige powder
UsesGallic Acid is a phenolic acid with antioxidant activity. Gallic acid was found to protect human cells against oxidative damage and showed cytotoxicity against cancer cells. Gallic Acid and its esters also show antiviral and antifungal activities.
Usesanti-hyperlipoproteinemic, selective, reversible, competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
UsesGallic acid monohydrate may be used as a standard in the photometric determination of total phenolics content by Folin-Ciocalteu method.
General DescriptionGallic acid monohydrate is a phenolic acid. A study of its crystalline structure reveals that it is planar with two intramolecular hydrogen bonds and five intermolecular hydrogen bonds. Gallic acid is of significant importance because of its antioxidant and anti-cancer activities. Infrared and Raman spectral studies of gallic acid have been reported.
Purification MethodsCrystallise gallic from water. The tri-O-acetyl derivative has m 172o (from MeOH), and the anilide has m 207o(from EtOH). [Beilstein 10 H 470, 10 IV 1993.]
Gallic acid monohydrate Preparation Products And Raw materials
Preparation ProductsGallic acid
Propyl gallate Gallic acid (Monohydrate or Anhydrous) ,GALLIC ACID (MONOHYDRATE OR ANHYDROUS) (3,4,5-TRIHYDROXYBENZOIC ACID ) Methylparaben Methyl gallate (-)-Epicatechin gallate 3-(Trifluoromethyl)benzoic acid MELIBIOSE 4-Hydroxybenzoic acid Salicylic acid Ethyl 2-(Chlorosulfonyl)acetate 2'-Hydroxy-3-phenylpropiophenone Ascoric Acid 3-Hydroxybenzoic acid Folic acid Butylparaben Pyrogallol 2,3,4-Trihydroxybenzoic acid Citric acid

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