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| | (R)-alpha,alpha-Diphenylmethylprolinol Basic information | | Reaction |
| Product Name: | (R)-alpha,alpha-Diphenylmethylprolinol | | Synonyms: | (2R)-(-)-2-[Diphenyl(hydroxy)methyl]-1-methylpyrrolidine, (-)-alpha,alpha-Diphenyl-N-methyl-D-prolinol;(2R)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol;(2R)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol,99%e.e.;(2R)-(-)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98%;[(2R)-1-methylpyrrolidin-2-yl]-diphenylmethanol;(2R)-(-)-N-Methyl-α;-diphenyl-2-pyrrolidinemethanol, min. 98%;α,α-Diphenyl-N-methyl-D-prolinol, 98%, ee: 98% | | CAS: | 144119-12-0 | | MF: | C18H21NO | | MW: | 267.37 | | EINECS: | 635-081-7 | | Product Categories: | Asymmetric Synthesis;Synthetic Organic Chemistry | | Mol File: | 144119-12-0.mol |  |
| | (R)-alpha,alpha-Diphenylmethylprolinol Chemical Properties |
| Melting point | 68-71 °C | | alpha | -52° (c=1, CHCl3) | | Boiling point | 406.8±25.0 °C(Predicted) | | density | 1.116±0.06 g/cm3(Predicted) | | refractive index | -55 ° (C=1, CHCl3) | | storage temp. | Sealed in dry,Room Temperature | | pka | 13.15±0.29(Predicted) | | form | Powder | | color | white to light-yellow | | optical activity | [α]20/D 55.0±4.0°, c = 1% in chloroform stab. with amylenes | | BRN | 1535407 | | CAS DataBase Reference | 144119-12-0(CAS DataBase Reference) |
| | (R)-alpha,alpha-Diphenylmethylprolinol Usage And Synthesis |
| Reaction |
- Chiral amino alcohol assisted asymmetric, enantioselective, aryl transfer of triphenylboroxin to a set of aryl aldehydes in the presence of chiral amino alcohols derived from (S)-proline.
- Pyrrolidinylmethanol compound used for the zinc-catalyzed addition of arylboronic acids to aromatic aldehydes, proceeding in high yields and high enantioselectivities (up to 98% ee).
| | Chemical Properties | white to off-white crystalline powder |
| | (R)-alpha,alpha-Diphenylmethylprolinol Preparation Products And Raw materials |
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