ChemicalBook Product Catalog Chemical Reagents Organic reagents Esters Ethyl compound Chlorodifluoroacetic acid ethyl ester

Chlorodifluoroacetic acid ethyl ester

Chlorodifluoroacetic acid ethyl ester Basic information
Product Name:Chlorodifluoroacetic acid ethyl ester
Synonyms:Ethyl chlorodifluoroacetate 98%;Ethyl 2-chloro-2,2-difluoroacetate;Ethyl chlorodifluoroethanoate;Difluorochloroacetic acid ethyl ester;Ethyl chlorodifluoroacetate, Chlorodifluoroacetic acid ethyl ester;Ethyl 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid ethyl ester;Ethyl chloroacetatetwo fluorine;Acetic acid,2-chloro-2,2-difluoro-, ethyl ester
CAS:383-62-0
MF:C4H5ClF2O2
MW:158.53
EINECS:206-850-0
Product Categories:C2 to C5;Carbonyl Compounds;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Esters;Pharmaceutical Intermediates
Mol File:383-62-0.mol
Chlorodifluoroacetic acid ethyl ester Structure
Chlorodifluoroacetic acid ethyl ester Chemical Properties
Boiling point 96-97.5 °C (lit.)
density 1.252 g/mL at 25 °C (lit.)
refractive index n20/D 1.358(lit.)
Fp 65 °F
storage temp. 2-8°C
solubility Chloroform (Sparingly), Ethyl Acetate (Sparingly)
form clear liquid
color Colorless to Almost colorless
Specific Gravity1.252
Sensitive Moisture Sensitive
BRN 1761413
CAS DataBase Reference383-62-0(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, chlorodifluoro-, ethyl ester (383-62-0)
Safety Information
Hazard Codes F,C,Xi
Risk Statements 11-34-20/21/22
Safety Statements 16-26-27-36/37/39-45
RIDADR UN 2924 3/PG 2
WGK Germany 3
Hazard Note Flammable
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29159000
MSDS Information
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Chlorodifluoroacetic acid ethyl ester English
ACROS English
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Chlorodifluoroacetic acid ethyl ester Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesEthyl chlorodifluoroacetate (ECDFA) may be used as a starting reagent in the synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols.
General DescriptionEthyl chlorodifluoroacetate (ECDFA) undergoes Reformatskii reaction with various aldehydes in DMF. It reacts with phenylacetylene to afford ethyl α,α?difluoro-4-phenyl-3-butenoates.
Chlorodifluoroacetic acid ethyl ester Preparation Products And Raw materials
Preparation Products6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE-->1-Bromo-4-(2,2,2-trifluoroethyl)benzene
Difluoroacetic acid Ethyl difluoroacetate ETHYL CHLOROFLUOROACETATE Chlorodifluoroacetic acid CHLORO-DIFLUORO-ACETIC ACID ALLYL ESTER METHYL CHLORODIFLUOROACETATE Ethyl fluoroacetate T-BUTYL CHLORODIFLUOROACETATE 2-Chloroethyl ethyl ether Difluorochloromethane CHLOROFLUOROACETIC ACID 1-CHLORO-1-FLUOROETHANE 1-Chloro-1,1-difluoroethane CHLORODIFLUOROACETIC ANHYDRIDE Chlorodifluoroacetic acid ethyl ester 2-CHLORO-2,2-DIFLUOROETHANOL Ethyl chloroacetate Methyl chloroacetate
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