Vanillyl alcohol

Vanillyl alcohol Basic information
Product Name:Vanillyl alcohol
Synonyms:3,4-Dihydroxybenzyl alcohol 3-Methyl ester;α,4-Dihydroxy-3-Methoxytoluene;2-Hydroxy-5-(hydroxymethyl)anisole, 4-Hydroxy-3-methoxybenzyl alcohol, Vanillyl alcohol;4-Hydroxy-3-Methoxybenzyl alcohol, 99% 50GR;3-Methoxy-4-hydroxybenzyl alcohol;Vanillic alcohol;4-HYDROXY-3-METHOXYBENZYL ALCOHOL, 98+%;4-Hydroxy-3-methoxybenzyl alcohol,99%
CAS:498-00-0
MF:C8H10O3
MW:154.16
EINECS:207-852-4
Product Categories:Inhibitors;Bifunctional Linkers;Linkers and Crosslinkers;Alcohols;Building Blocks;C7 to C8;Chemical Biology;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Benzhydrols, Benzyl & Special Alcohols;498-00-0
Mol File:498-00-0.mol
Vanillyl alcohol Structure
Vanillyl alcohol Chemical Properties
Melting point 110-117 °C (lit.)
Boiling point 237.52°C (rough estimate)
density 1.1690 (rough estimate)
refractive index 1.4620 (estimate)
FEMA 3737 | VANILLYL ALCOHOL
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Methanol
form Fine Crystalline Powder
pka9.75±0.18(Predicted)
color Off-white to beige
Odorat 100.00 %. sweet creamy vanilla caramellic coconut graham cracker tonka milky powdery
Odor Typecreamy
Water Solubility Soluble in 95% ethanol (5 %), water, and oils.
JECFA Number886
BRN 1910044
Stability:Stable. Incompatible with strong oxidizing agents, strong acids.
LogP0.42
CAS DataBase Reference498-00-0(CAS DataBase Reference)
NIST Chemistry Reference4-Hydroxy-3-methoxybenzyl alcohol(498-00-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
Hazard Note Irritant
HS Code 29095090
MSDS Information
ProviderLanguage
Vanillyl alcohol English
SigmaAldrich English
ACROS English
ALFA English
Vanillyl alcohol Usage And Synthesis
Description4-hydroxy-3-methoxybenzyl alcohol (also known as vanillyl alcohol) is often used as a deodorant component that is active in preventing the formation of body odor. It can also be used as a flavoring agent. Recent studies have also demonstrated that it has certain pharmacological effects. For example, it has been confirmed that it has certain neuro-protective effects through suppressing the oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells, making it a potential candidate for the treatment of neurodegenerative diseases such as Parkinson’s disease.
Chemical Propertiescrystalline white to off-white powder
Chemical PropertiesVanillyl alcohol has a mild, sweet, balsamic, vanilla-like odor.
UsesUsed as a flavoring agent. Other possible uses, vanilla, coconut, cream and other dairy nuances, coumarin.
DefinitionChEBI: Vanillyl alcohol is a monomethoxybenzene that is 2-methoxyphenol substituted by a hydroxymethyl group at position 4. It has a role as a plant metabolite. It is a member of guaiacols and a member of benzyl alcohols.
Taste threshold valuesSweet, creamy and milky with a slightly powdery mouthfeel.
General DescriptionVanillyl alcohol belongs to the phenolic group of compounds which are widely used as oxidants in food products.
Biochem/physiol ActionsOdor at 1.0%: sweet creamy, phenolic, vanilla and coconut-like with slight brown and coumarinic nuances.
ReferencesBrune, I, et al. "Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression." Journal of Biotechnology 127.1(2006):21-33.
Hsu, Lun Chung, Z. H. Wen, and K. Y. Lee. "Use of vanillyl alcohol for the treatment of Parkinson's disease." (2009).
Kim, I. S., D. K. Choi, and H. J. Jung. "Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells." Molecules 16.7(2011):5349.

Vanillyl alcohol Preparation Products And Raw materials
Preparation Products4-HYDROXY-3-METHOXYPHENYLACETONITRILE-->METHOXYBENZOQUINONE-->4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE-->1-(4-hydroxy-3-methoxyphenyl)decan-5-one-->m-Anisyl alcohol-->2-Hydroxy-3-methoxybenzyl alcohol-->p-Cresol
2-HYDROXY-5-METHOXYBENZYL ALCOHOL (+)-Bicuculline 5-BROMO-2-HYDROXY-3-METHOXYBENZYL ALCOHOL 2-BROMO-3-HYDROXY-4-METHOXYBENZYL ALCOHOL 3-CHLORO-4-HYDROXY-5-METHOXYBENZYL ALCOHOL, 98% 5-Hydroxy-3-methoxybenzyl alcohol α-(aminomethyl)-4-hydroxy-3-methoxybenzyl alcohol hydrochloride,ALPHA-(AMINOMETHYL)-4-HYDROXY-3-METHOXYBENZYL ALCOHOL HYDROCHLORIDE 3,4,5-Trimethoxybenzyl alcohol 2-BROMO-4-HYDROXY-5-METHOXYBENZYL ALCOHOL 4-ETHOXYCARBONYLOXY-3,5-DIMETHOXYBENZOIC ACID 5-BROMO-4-HYDROXY-3-METHOXYBENZYL ALCOHOL 3-hydroxy-2-methoxybenzyl alcohol 3-Hydroxy-4,5-dimethoxybenzoic acid 3-FLUORO-4-HYDROXY-5-METHOXYBENZYL ALCOHOL Vanillyl butyl ether 2,3,4-TRIMETHOXYBENZYL ALCOHOL 4-BENZYLOXY-3-METHOXYBENZYL ALCOHOL CHLOROPHOSPHONAZO III

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.