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| | FLUCYTHRINATE Basic information |
| | FLUCYTHRINATE Chemical Properties |
| Melting point | <25℃ | | Boiling point | 108℃ (0.35mmHg) | | density | 1.189 g/cm3 (22℃) | | vapor pressure | 1.2×10-6 Pa (25 °C) | | refractive index | 1.541 (589.3 nm 25℃) | | Fp | -18 °C | | storage temp. | 2-8°C | | Water Solubility | 0.5 mg l-1 (22 °C) | | form | neat | | Specific Gravity | 1.189 (22℃) | | BRN | 2195795 | | CAS DataBase Reference | 70124-77-5(CAS DataBase Reference) | | EPA Substance Registry System | Flucythrinate (70124-77-5) |
| Hazard Codes | T,N,Xn,F | | Risk Statements | 20/21-25-50/53-67-65-38-11 | | Safety Statements | 36/37-45-60-61-62 | | RIDADR | UN 2810 6.1/PG 3 | | WGK Germany | 3 | | RTECS | CY1578620 | | HS Code | 29269090 | | Hazardous Substances Data | 70124-77-5(Hazardous Substances Data) | | Toxicity | LC50 (96-hour) for rainbow trout 0.32 μg/L, bluegill sun?sh 0.71 μg/L, channel cat?sh 0.51 μg/L, sheepshead minnow 1.6 μg/L (Hartley and Kidd, 1987), estuarine mysid 0.008 μg/L, pink shrimp 0.22 μg/L and sheepshead minnow 1.1 μg/L (Schimmel et al., 1983); acute oral LD50 for male and female rats is 81 and 67 mg/kg, respectively (Hartley and Kidd, 1987). |
| | FLUCYTHRINATE Usage And Synthesis |
| Uses | Nonsystemic insecticide. | | Uses | Flucythrinate controls a wide range of insects on cotton, fruit trees,
vines, citrus, bananas, pineapples, olives, coffee, cocoa, hops, vegetables,
soyabeans, cereals, alfalfa, sugar beet, sunflowers and tobacco. | | General Description | Flucythrinate belongs to the class of synthetic pyrethroids, primarily used to control Heliothis spp. in cotton and other insect pests in agricultural crops. | | Agricultural Uses | Insecticide, Acaricide: Not approved for use in EU countries. Not currently registered in the U.S. Flucythrinate is a synthetic pyrethroid used to control pests in apples, cabbage, head lettuce, pears, corn and cotton, but it was used primarily on cotton.
| | Trade name | AASTAR®[C]; CYBOLT®; CYTHRIN®;
FUCHING JUJR®; GUARDIAN®[C]; PAYOFF®[C];
STOCK GUARD®; TOMAHAWK® | | Pharmacology | Flucythrinate
is the (S)-2-(4-difluoromethoxyphenyl)-3-methylbutyrate
analog of fenvalerate, partially resolved. Its insecticide
action is approximately two times higher compared
with fenvalerate (138,142). | | Environmental Fate | Surface Water. The half-life of ?ucythrinate in an estuarine environment is 34 days (Schimmel et al., 1983).
Chemical/Physical. Hydrolyzes in aqueous solutions forming acetic acid and other compounds.
| | Metabolic pathway | Flucythrinate is an analogue of fenvalerate and would be expected to
have a similar fate. | | Degradation | Flucythrinate is a stable compound but it is readily hydrolysed at alkaline
pH to afford 2-(4-difluoromethoxyphenyl)-3-methylbutyric acid (2),
3PBAl(3) and cyanide ion. Its DT50 values at 27 °C are 52 days (pH 5) and
6.3 days (pH 9). It undergoes aqueous and soil surface photolysis with
DT50 values of 1-4 days and <2 days, respectively. The products formed
under aqueous conditions were 2 and 3. Compound 3 was oxidised to
3PBA (4) and reduced to 3PBAlc (5). The α-carbamoyl (amide) derivative
(6) of 3PBAlc was also detected. On soil surfaces, products were similar
with the exceptions that 3PBA was not formed and the α-amide (7) and
a-carboxy derivative (8) were formed. These are usually considered to be
products of thermal degradation (Dureja and Chattopadhyay, 1995). |
| | FLUCYTHRINATE Preparation Products And Raw materials |
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