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8-BROMOADENOSINE

8-BROMOADENOSINE Basic information
Product Name:8-BROMOADENOSINE
Synonyms:8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE;8-BROMOADENOSINE;6-AMINO-8-BROMOPURINE RIBOSIDE;(2R,3R,4S,5R)-2-(6-AMINO-8-BROMO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;8-BROMOADENOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM;8-BROMO-D-ADENOSINE;6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside;8-Bromoadenosine,98%
CAS:2946-39-6
MF:C10H12BrN5O4
MW:346.14
EINECS:220-959-0
Product Categories:Pyridines, Pyrimidines, Purines and Pteredines;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
Mol File:2946-39-6.mol
8-BROMOADENOSINE Structure
8-BROMOADENOSINE Chemical Properties
Melting point 210-212 °C (dec.)(lit.)
Boiling point 717.7±70.0 °C(Predicted)
density 1.8171 (rough estimate)
refractive index 1.6400 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka12.89±0.70(Predicted)
form powder
color white
Water Solubility Soluble in DMSO, and DMF. Insoluble in water.
Sensitive Air Sensitive
BRN 627737
CAS DataBase Reference2946-39-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-22
WGK Germany 3
F 10-23
HS Code 2934 99 90
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
8-BROMOADENOSINE Usage And Synthesis
Description8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.
Chemical PropertiesOff-White Solid
Uses8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.
DefinitionChEBI: 8-Bromoadenosine is a purine nucleoside.
8-BROMOADENOSINE Preparation Products And Raw materials
Preparation Products8-CHLOROADENOSINE-->8-BROMOADENOSINE 5'-MONOPHOSPHATE-->Adenosine, 8-[(3-aminopropyl)amino]- (9CI)-->8-BROMOINOSINE-->8-Azidoadenosine-->Adenosine
8-BROMO-2'-O-MONOBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 8-bromoadenosine 5'-triphosphate sodium 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT HYDRATE 2-(6-AMINO-8-BROMO-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL 8-BROMO-ADENOSINE-5'-DIPHOSPHATE, SODIUM SALT 8-bromoadenosine 5'-monophosphate*free acid,8-BROMOADENOSINE 5'-MONOPHOSPHATE BETA-BROMOADENOSINE-5'-TRIPHOSPHATE SODIUM 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 8-BROMO-CADP-RIBOSE (7-DIMETHYLAMINOCOUMARIN-4-YL)METHYL-8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE, HYDRATE 8-BROMO-ADENOSINE-5'-[(BETA,GAMMA)-IMIDO]TRIPHOSPHATE, SODIUM SALT 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT 8-BROMOADENOSINE-2',3,5'-TRIACETATE,2',3',5'-TRI-O-ACETYL-8-BROMOADENOSINE [6,7-BIS (CARBOXYMETHOXY)COUMARIN-4-YL]METHYL-8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE, 2,5-HYDRATE 8-BROMOADENOSINE 8-BROMO-2'-MONOBUTYRYLADENOSINE-3'-5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER
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