Daidzin

Daidzin Basic information

Product Name:	Daidzin
Synonyms:	4h-1-benzopyran-4-one,7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydro;7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydroxy-4h-1-benzopyran-4;7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydroxy-4h-1-benzopyran-4-on;7,4-dihydroxyisoflavone7-glucoside;daidzoside;GLUCOSYL-7-DAIDZEIN;DAIDZEIN-7-GLUCOSIDE;DAIDZEIN-7-O-BETA-D-GLUCOPYRANOSIDE
CAS:	552-66-9
MF:	C21H20O9
MW:	416.38
EINECS:	611-245-3
Product Categories:	Inhibitors;inhibitor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;pharmacetical;The group of Daidzin;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Glucuronides;Heterocycles;standardized herbal extract
Mol File:	552-66-9.mol

Daidzin Chemical Properties

Melting point	234-236°C
alpha	-24 º (C=0.1g/100ml,dimethylsulfoxide)
Boiling point	727.6±60.0 °C(Predicted)
density	1.572±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO (Slightly, Sonicated), Methanol (Slightly, Heated)
form	neat
pka	9.65±0.30(Predicted)
color	White to Off-White
λmax	297nm(lit.)
BRN	59741
LogP	0.369 (est)
CAS DataBase Reference	552-66-9(CAS DataBase Reference)

Safety Information

Safety Statements	24/25
WGK Germany	3
RTECS	DJ3094000
F	10
HS Code	29389090
Toxicity	mouse,LD50,intraperitoneal,> 2gm/kg (2000mg/kg),Pharmaceutical Chemistry Journal Vol. 13, Pg. 51, 1979.

MSDS Information

Provider	Language
SigmaAldrich	English

Daidzin Usage And Synthesis

Chemical Properties	White Powder
Uses	A derivative of Daidzein. Inhibitor
Uses	A metabolite of isoflavone derivatives. A derivative of Daidzin. Inhibitor.
Definition	ChEBI: Daidzein 7-O-beta-D-glucoside is a glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic). It has a role as a plant metabolite. It is a hydroxyisoflavone, a monosaccharide derivative and a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a daidzein.
General Description	Daidzin is a plant isoflavone glycoside and a potent inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I).
Biochem/physiol Actions	Daidzin was the most potent isoflavone glycoside tested in modulating differentiation of bone marrow stromal cells toward osteoblasts and away from adipocytes.
target	IL Receptor \| ALDH2

Daidzin Preparation Products And Raw materials

2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Lecithin Alkyl polyglucoside Shiny Bugle wood CALYCOSIN 7-GLUCOSIDE AKOS 238-07 6''-O-ACETYLGLYCITIN 6''-O-ACETYLGENISTIN WISTIN PSEUDOBAPTIGENIN-7-GLUCOSIDE 6''-O-ACETYLDAIDZIN Daidzein GENISTEIN 7-O-APIOSYL-(1,6)-GLUCOSIDE kakkalide Soy protein isolate Daidzin 7-HYDROXYFLAVONE Genistin

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