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| | DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Basic information |
| | DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Chemical Properties |
| Melting point | 105-108 °C(lit.) | | Boiling point | 372.6±37.0 °C(Predicted) | | density | 1.3137 (rough estimate) | | refractive index | 1.5500 (estimate) | | pka | -0.53±0.10(Predicted) | | form | Crystalline Powder | | color | Slightly yellow to beige-yellow | | CAS DataBase Reference | 4815-30-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-60-37 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29349990 |
| | DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Usage And Synthesis |
| Chemical Properties | slightly yellow to beige-yellow crystalline powder | | Uses | Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents. |
| | DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Preparation Products And Raw materials |
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