4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE

4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE Basic information

Product Name:	4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE
Synonyms:	4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE;4-METHYL-2-(METHYLTHIO)PYRIMIDINE;4-Methyl-2-Thiomethyl Pyrimidine;Pyrimidine, 4-methyl-2-(methylthio)- (6CI, 8CI, 9CI);SPECS AR-527/42979548;4-Methyl-2-(methylthio)pyrimidine ,97%;Pyrimidine, 4-methyl-2-(methylthio)-;4-Methyl-2-(methylsulphanyl)pyrimidine
CAS:	14001-63-9
MF:	C6H8N2S
MW:	140.21
EINECS:
Product Categories:	Heterocycle-Pyrimidine series;PYRIMIDINE;THIOL;Building Blocks;Heterocyclic Building Blocks;Pyrimidines
Mol File:	14001-63-9.mol

4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE Chemical Properties

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE Usage And Synthesis

Chemical Properties	Colorless to yellow to red liquid
Uses	4-Methyl-2-(methylthio)pyrimidine is used as a reagent to prepare pyrazolopyrimidines and pyrazolotriazines, both of which display potent activity against herpes viruses. 4-Methyl-2-(methylthio)pyrimidine is also used as a starting material to synthesize 4-substituted-2-aminopyrimidines (e.g. 2-amino-4-ethylpyridine [A609500]), novel c-Jun N-terminal kinase (JNK) inhibitors.

4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE Preparation Products And Raw materials

Raw materials	Ethanol-->Hydrochloric acid-->Iodomethane-->Thiourea-->Acetylacetaldehyde dimethyl acetal
Preparation Products	2(1H)-Pyrimidinone, 4-methyl-, hydrazone (9CI)-->2-[2-(METHYLSULFANYL)-4-PYRIMIDINYL]-1-[3-(TRIFLUOROMETHYL)PHENYL]-1-ETHANONE-->2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone-->2-(2-(methylthio)pyrimidin-4-yl)-3-oxopropanenitrile

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