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| | (R)-(-)-3-Hydroxytetrahydrofuran Basic information |
| | (R)-(-)-3-Hydroxytetrahydrofuran Chemical Properties |
| alpha | -18.5 º (c=2 MeOH) | | Boiling point | 181 °C (lit.) | | density | 1.097 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.45(lit.) | | Fp | 180 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform, Methanol (Slightly) | | pka | 14.49±0.20(Predicted) | | form | Liquid | | color | Clear colorless | | Specific Gravity | 1.097 | | optical activity | [α]20/D 18°, c = 2.4 in methanol | | InChI | InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m1/s1 | | InChIKey | XDPCNPCKDGQBAN-SCSAIBSYSA-N | | SMILES | O1CC[C@@H](O)C1 | | CAS DataBase Reference | 86087-24-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | NA 1993 / PGIII | | WGK Germany | 3 | | HS Code | 29321900 |
| | (R)-(-)-3-Hydroxytetrahydrofuran Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | (R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant | | Uses | (R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors. |
| | (R)-(-)-3-Hydroxytetrahydrofuran Preparation Products And Raw materials |
| Raw materials | 3-Furanol, tetrahydro-, 3-acetate-->Dihydrofuran-3(2H)-one-->3-Hydroxytetrahydrofuran-->(R)-4-CHLORO-1,3-BUTANEDIOL-->(R)-(+)-1,2,4-BUTANETRIOL-->but-3-en-1-yl 4-methylbenzene-1-sulfonate-->(S)-1,2,4-Butanetriol-->2,3-Dihydrofuran | | Preparation Products | Furan, tetrahydro-3-iodo-, (3S)--->(S)-3-P-MESYLOXYTETRAHYDROFURAN |
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