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| | 5,7-Dichloro-8-hydroxyquinoline Basic information |
| Product Name: | 5,7-Dichloro-8-hydroxyquinoline | | Synonyms: | 5,7-Dichlor-8-hydroxychinolin;5,7-Dichloro-8-hydroquinoline;5,7-Dichloro-8-hydroxyquinolin;5,7-Dichloro-8-oxychinolin;5,7-Dichloro-8-oxyquinoline;5,7-dichloro-8-quinolino;5,7-Dichlorooxine;5,7-Dichloroxine | | CAS: | 773-76-2 | | MF: | C9H5Cl2NO | | MW: | 214.05 | | EINECS: | 212-258-3 | | Product Categories: | CINAZYN;Building Blocks;C8 to C10;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Quinolines, Quinazolines and derivatives;Haloquinolines;Hydroxyquinolines;Quinolines | | Mol File: | 773-76-2.mol |  |
| | 5,7-Dichloro-8-hydroxyquinoline Chemical Properties |
| Melting point | 178-180 °C (lit.) | | Boiling point | 305.47°C (rough estimate) | | density | 1.3320 (rough estimate) | | refractive index | 1.5500 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated) | | pka | 2.30±0.30(Predicted) | | form | Fluffy Powder | | color | Light beige | | Merck | 14,2175 | | BRN | 153606 | | Stability: | Light Sensitive | | CAS DataBase Reference | 773-76-2(CAS DataBase Reference) | | NIST Chemistry Reference | 8-Quinolinol, 5,7-dichloro-(773-76-2) | | EPA Substance Registry System | 8-Quinolinol, 5,7-dichloro- (773-76-2) |
| | 5,7-Dichloro-8-hydroxyquinoline Usage And Synthesis |
| Chemical Properties | light beige fluffy powder | | Uses | H1 antihistamine | | Uses | Analytical reagent. | | Uses | Chloroxine, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug. | | Indications | Chloroxine (Capitrol) shampoo contains a synthetic antibacterial compound
similar to the hydroxyquinoline compounds used in dermatology for many
years. | | Definition | ChEBI: Quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. An synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp. | | Brand name | Capitrol (Westwood-
Squibb). | | Purification Methods | Crystallise the dichloro-oxine from acetone/EtOH. [Beilstein 21 H 95.] |
| | 5,7-Dichloro-8-hydroxyquinoline Preparation Products And Raw materials |
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