Vindoline

Vindoline Basic information
Product Name:Vindoline
Synonyms:aspidospermidine-3-carboxylicacid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-me;thoxy-1-methyl-,methylester,(2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha);vindolin;(2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester;VINDOLINE;Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-;(2,3,4,5a,12,19a)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic Acid Methyl Ester;NSC 91994
CAS:2182-14-1
MF:C25H32N2O6
MW:456.53
EINECS:218-558-0
Product Categories:Alkaloids;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Biochemicals
Mol File:2182-14-1.mol
Vindoline Structure
Vindoline Chemical Properties
Melting point 163-1650C
alpha D20 -18° (chloroform); D27 +42° (chloroform)
Boiling point 569.8±50.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka5.5 in 66% DMF (Moza, Trojánek)
form White to off-white crystalline powder.
color White to Off-White
Safety Information
Hazard Codes Xn
Risk Statements 68
Safety Statements 36/37-24/25
HS Code 29339900
Vindoline Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesVindoline is a novel antitumor agent.
DefinitionChEBI: Vindoline is a vinca alkaloid, an alkaloid ester, an organic heteropentacyclic compound, a methyl ester, an acetate ester, a tertiary amino compound and a tertiary alcohol. It is a conjugate base of a vindolinium(1+).
Vindoline Preparation Products And Raw materials
Preparation ProductsVinblastine sulfate
(R)-3-T-BUTYL-BETA-ALANINE L-β-Homo-Tyr-OH.HCl 3-AMINO-4-(4-METHOXY-PHENYL)-BUTYRIC ACID 3-AMINO-4-ETHYL-OCTANOIC ACID (S)-2-Hydroxy-4-phenylbutyric acid VINDOLINE(REAGENT / STANDARD GRADE) L-beta-Homophenylalanine hydrochloride (S)-3-AMINO-4-(4-METHOXYPHENYL)BUTANOIC ACID (2S,3S)-3-AMINO-2-HYDROXYHEPTANOIC ACID (S)-3-(Phenylamino)butanoic acid DL-3-T-BUTYL-BETA-ALANINE (R)-2-AMINO-5-DIETHYLAMINOPENTANE, (2S,3S)-3-AMINO-2-HYDROXYHEXANOIC ACID 3-AMINO-4-PHENYL-PENTANOIC ACID 3-[(3-METHOXY-PHENYL)-METHYL-AMINO]-PROPIONIC ACID (2S,3S)-3-AMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID (R)-HOMO-BETA-VALINE CIS-2-AMINO-1-CYCLOHEXANECARBOXYLIC ACID

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