ChemicalBook Product Catalog Biochemical Engineering Inhibitors Endocrinology & Hormones GPR antagonist OC000459

OC000459

OC000459 Basic information
Product Name:OC000459
Synonyms:OC000459;2-(5-fluoro-2-Methyl-3-(quinolin- 2-ylMethyl)-1H-indol-1-yl)acetic acid;5-Fluoro-2-Methyl-3-quinolin-2-ylMethylindo-1-yl)-acetic(OC000459);[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid;5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid;OC000495;(5-Fluoro-3-isoquinolin-3-ylMethyl-2-Methyl-indol-1-yl)-acetic acid;1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-
CAS:851723-84-7
MF:C21H17FN2O2
MW:348.37
EINECS:
Product Categories:Inhibitors
Mol File:851723-84-7.mol
OC000459 Structure
OC000459 Chemical Properties
Boiling point 574.4±50.0 °C(Predicted)
density 1.29
storage temp. Store at -20°C
solubility DMF: 0.5 mg/ml; DMSO: 1.1 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form A crystalline solid
pka4.08±0.10(Predicted)
Safety Information
MSDS Information
OC000459 Usage And Synthesis
UsesOC000459 is a CRTH2 antagonist which helps in the treatment of allergies, reducing nasal and ocular symptoms in subjects exposed to allergens.
OC000459 Preparation Products And Raw materials
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