N-methyl-2-sulfanylbenzamide

N-methyl-2-sulfanylbenzamide Basic information
Product Name:N-methyl-2-sulfanylbenzamide
Synonyms:N-methyl-2-sulfanylbenzamide;BenzaMide, 2-Mercapto-N-Methyl-;2- Mercapto-N-MethyllbenzaMide;2-MERCAPTO-N-METHYL BENZAMIDE(RE-EXPORTWIDE B/E.NO:2513786 DT 08.09.2015);N-methyl-2-sulfanylbenzamide ISO 9001:2015 REACH;1.2-mercapto-N-methylbenzamide;Axitinib 2-Mercapto N-Methyl Benzamide;TIANFU CHEM N-methyl-2-sulfanylbenzamide
CAS:20054-45-9
MF:C8H9NOS
MW:167.23
EINECS:633-825-5
Product Categories:Intermediate
Mol File:20054-45-9.mol
N-methyl-2-sulfanylbenzamide Structure
N-methyl-2-sulfanylbenzamide Chemical Properties
Melting point 94-96 °C
Boiling point 326.2±25.0 °C(Predicted)
density 1.174
storage temp. 2-8°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka5.89±0.43(Predicted)
form Solid
color Off-White to Pale Beige
Stability:Air Sensitive
LogP1.360 (est)
Safety Information
HS Code 2930909899
MSDS Information
N-methyl-2-sulfanylbenzamide Usage And Synthesis
DescriptionN-methyl-2-sulfanylbenzamide is an axitinib intermediate.
Uses2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Application2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
N-methyl-2-sulfanylbenzamide Preparation Products And Raw materials
Preparation ProductsAxitinib Impurity B-->BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-
2-Aminoethylmethylsulfone hydrochloride (E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 3-Iodo-6-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 3-Iodo-6-nitroindazole Lapatinib ditosylate (E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 6-Nitroindazole

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