Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-

Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Basic information
Product Name:Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-
Synonyms:Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-;R-2-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethyl silyl)oxy]Methyl]-Pyrrolidine;(R)-2-[(Bis(3,5-bis(trifluoroMethyl)phenyl)]triMethylsilanyloxy)Methyl]pyrrolidine;(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine;(R)-alpha,alpha-Bis[3,5-bis(trifluoroMethyl)phenyl]-2-pyrrolidineMethanol triMethylsilyl ether technical grade;(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether;(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]- [(trimethylsilyl)oxy]methyl]pyrrolidine,99%e.e.;[bis[3,5-bis(trifluoromethyl)phenyl]-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
CAS:908303-26-4
MF:C24H23F12NOSi
MW:597.51
EINECS:
Product Categories:
Mol File:908303-26-4.mol
Pyrrolidine,  2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-,  (2R)- Structure
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Chemical Properties
Melting point 46-55°C
Boiling point 382.4±37.0 °C(Predicted)
density 1.319±0.06 g/cm3(Predicted)
Fp >110℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka9.34±0.10(Predicted)
form Solid
color White to Off-White
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
MSDS Information
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Usage And Synthesis
UsesCatalyst involved in:
  • Cyclocondensation of enals with methylenepyrrolidines
  • Organocatalytic additions of β-ketosulfoxides to conjugated aldehydes
  • Organocatalytic aza-Michael reactions
  • Stereoselective propargylic alkylation of propargylic esters with aldehydes
  • Epoxidation or aziridination of α,β-unsaturated aldehydes and Feist-Benary reactions of 1,3-dicarbonyls
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Preparation Products And Raw materials
Raw materials(R)-bis(3,5-bis(trifluoroMethyl)phenyl)(pyrrolidin-2-yl)Methanol-->Trimethylsilyl trifluoromethanesulfonate
(R)-(+)-2-[Bis(3,5-dimethylphenyl)hydroxymethyl]pyrrolidine Pyrrolidine, 2-[bis(3,5-dimethylphenyl)[(trimethylsilyl)oxy]methyl]-, (2R)- (R)-bis(3,5-bis(trifluoroMethyl)phenyl)(pyrrolidin-2-yl)Methanol (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether (R)-2-(bis(3,5-bis(trifluoroMethyl)phenyl)(tert-butyldiMethylsilyloxy)Methyl)pyrrolidine R-2-[bis[3,5-bis(trifluoroMethyl)phenyl] [(triethylsilyl)oxy]Methyl]-Pyrrolidine

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