ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Piperazine compounds 1-(Tetrahydro-2-furoyl)piperazine

1-(Tetrahydro-2-furoyl)piperazine

1-(Tetrahydro-2-furoyl)piperazine Basic information
Product Name:1-(Tetrahydro-2-furoyl)piperazine
Synonyms:RARECHEM AH CK 0199;(TETRAHYDROFURAN-2-YL)(PIPERAZIN-1-YL)METHANONE;N-(2-TETRAHYDROFUROYL)PIPERAZINE;N-(TETRAHYDRO-2-FUROYL)-PIPERAZINE;PIPERAZIN-1-YL-(TETRAHYDRO-FURAN-2-YL)-METHANONE;TIMTEC-BB SBB005794;1-(2-TETRAHYDROFUROYL)-PIPERAZINE;1-(TETRAHYDRO-2-FUROYL)PIPERAZINE
CAS:63074-07-7
MF:C9H16N2O2
MW:184.24
EINECS:613-137-1
Product Categories:API intermediates;PHARMACEUTICAL INTERMEDIATES
Mol File:63074-07-7.mol
1-(Tetrahydro-2-furoyl)piperazine Structure
1-(Tetrahydro-2-furoyl)piperazine Chemical Properties
Boiling point 140 °C (1.5002 mmHg)
density 1.17
refractive index 1.5195-1.5215
Fp 120-125°C/0.2mm
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Viscous Liquid
pka8.37±0.10(Predicted)
color Colorless to yellow
Water Solubility Fully miscible in water.
BRN 880578
CAS DataBase Reference63074-07-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-36
Safety Statements 37/39-26-37
WGK Germany 3
Hazard Note Irritant
HS Code 29349990
MSDS Information
ProviderLanguage
ACROS English
ALFA English
1-(Tetrahydro-2-furoyl)piperazine Usage And Synthesis
Chemical Propertiescolorless to yellow viscous liquid
Uses1-?(Tetrahydro-?2-?furoyl)?-?piperazine (Terazosin EP Impurity N) has been used as a reactant for the preparation of pyrazol-3-propanoic acid derivatives as inhibitors of leukotriene biosynthesis in human neutrophils.
DefinitionChEBI: 1-(Tetrahydro-2-furoyl)piperazine is a member of phytanoyl-CoAs.
1-(Tetrahydro-2-furoyl)piperazine Preparation Products And Raw materials
Raw materialsMethyl 2-tetrahydrofuroate-->2-Tetrahydrofuroic acid-->Piperazine-->Hexamethyldisilazane
Terazosin impurity Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone [4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin IMpurity J [4-(4-AMino-6-hydroxy-7-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone N-(2-TETRAHYDRO-2-FUROYL)PIPERAZINE 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine TERAZOSIN HYDROCHLORIDE MONOHYDRATE EB-47 6-CHLORO-4-PHENYL-3-(3-(4-(TETRAHYDROFURAN-2-CARBONYL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)QUINOLIN-2(1H)-ONE 1,3-DIMETHYL-8-[4-(TETRAHYDROFURAN-2-YLCARBONYL)PIPERAZIN-1-YL]-3,7-DIHYDRO-1H-PURINE-2,6-DIONE 1-(tetrahydro-2-furoyl)piperazine hydrochloride 7-BENZYL-1,3-DIMETHYL-8-[4-(TETRAHYDROFURAN-2-YLCARBONYL)PIPERAZIN-1-YL]-3,7-DIHYDRO-1H-PURINE-2,6-DIONE 1-(Tetrahydro-2-furoyl)piperazine EB-47 DIHYDROCHLORIDE DIHYDRATE N-(TETRAHYDRO-2-FUROYL)-PIPERAZINE HBR Terazosin hydrochloride
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