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| | 5-INDANOL Basic information | | Uses |
| | 5-INDANOL Chemical Properties |
| Melting point | 51-53 °C (lit.) | | Boiling point | 255 °C (lit.) | | density | 0.8540 (rough estimate) | | refractive index | 1.5630 (estimate) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | 6.3g/l | | form | powder to crystal | | pka | 10.37±0.20(Predicted) | | color | slightly brown | | BRN | 1936314 | | CAS DataBase Reference | 1470-94-6(CAS DataBase Reference) | | EPA Substance Registry System | 5-Indanol (1470-94-6) |
| Hazard Codes | Xn,Xi | | Risk Statements | 21-20/21/22 | | Safety Statements | 36/37-36 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | NK7525000 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29062900 |
| | 5-INDANOL Usage And Synthesis |
| Uses | 5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin; a compound which has been shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic. | | Chemical Properties | light brown to grey-brown crystalline powder or | | Uses | 5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin (S635000); a compound which has been shown to reduce blood pressure in mammals and also has been used as a b-lactam antibiotic. | | Definition | ChEBI: A member of the class of phenols that is indan which has been hydroxylated at position 5. | | Purification Methods | Crystallise 5-hydroxyindane from pet ether (m 56o) or pentane (m 59-60o). It has UV with max at 283.5nm (cyclohexane). The 3,5-dinitrobenzoyl derivative has m 156o. [Beilstein 6 III 2428, 6 IV 3829.] |
| | 5-INDANOL Preparation Products And Raw materials |
| Raw materials | Methanesulfonic acid, 1,1,1-trifluoro-, 2,3-dihydro-1H-inden-5-yl ester-->Indan-->4-INDANOL | | Preparation Products | 2,3,3a,4,5,6,7,7a-octahydro-1H-inden-5-ol-->Acetic acid, 2-[(2,3-dihydro-1H-inden-5-yl)oxy]-, ethyl ester-->5-(2-bromoethoxy)-2,3-dihydro-1H-indene |
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