3,4-Dimethoxy-L-phenylalanine

3,4-Dimethoxy-L-phenylalanine Basic information
Product Name:3,4-Dimethoxy-L-phenylalanine
Synonyms:(S)-3,4-DIMETHOXY-PHENYLALANINE;(S)-2-AMINO-3-(3,4-DIMETHOXY-PHENYL)-PROPIONIC ACID;TYROSINE, 3-METHOXY-O-METHYL-;3,4-DIMETHOXY-L-PHENYLALANINE;H-PHE[3,4-(OME) 2]-OH;H-PHE(3,4-DIMETHOXY)-OH;H-TYR(3-OME,4-ME)-OH;H-3,4-DIMETHOXY-PHE-OH
CAS:32161-30-1
MF:C11H15NO4
MW:225.24
EINECS:626-580-0
Product Categories:Amino Acids & Derivatives;Aromatics;Peptide Synthesis;Phenylalanine Derivatives;Unnatural Amino Acid Derivatives
Mol File:32161-30-1.mol
3,4-Dimethoxy-L-phenylalanine Structure
3,4-Dimethoxy-L-phenylalanine Chemical Properties
Melting point 254-257 °C(lit.)
alpha -5 º (c=4 in 1 M HCl)
Boiling point 374.3±42.0 °C(Predicted)
density 1.214±0.06 g/cm3(Predicted)
storage temp. Store at 0°C
solubility Aqueous Acid (Slightly, Heated Sonicated), Aqueous Base (Slightly), Water (Slightly)
form Solid
pka2.23±0.20(Predicted)
color White to Off-White
optical activity[α]22/D 5°, c = 4 in 1 M HCl
Sensitive Air Sensitive
Stability:Hygroscopic, Temperature Sensitive
CAS DataBase Reference32161-30-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37
WGK Germany 3
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
3,4-Dimethoxy-L-phenylalanine Usage And Synthesis
Chemical PropertiesWhite Solid
UsesDOPA intermediate.
Uses3-(3,4-Dimethoxyphenyl)-L-alanine can be used as a reactant to synthesize (2S)-2-amino-3-[3,4-di(methoxy)phenyl]propan-1-ol (β-amino alcohol) for use as a key intermediate to prepare tetracyclic core of the Erythrina alkaloids.
3,4-Dimethoxy-L-phenylalanine Preparation Products And Raw materials
Preparation Products(S)-3,4-DIMETHOXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE
3-(3,4-DIBENZYLOXYPHENYL)-SERINE Phenprobamate 3-O-METHYL-4-O-BOC-6-TRIMETHYLSTANNYL-L-DOPA Dimethoxy L-Phenylalanine FMOC-3,4-DIMETHOXY-L-PHENYLALANINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-(3,4-DIMETHOXY)-L-PHENYLALANINE Benzyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate L-Alanine MOEXIPRILAT HYDRATE Dimethyl methyldopa L-Alanine 3,4-DIMETHOXY-5-HYDROXYPHENYLALANINE (S)-2-AMINO-3-(2,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID L-TYROSINE, 5-[[(1,1-DIMETHYLETHOXY)CARBONYL]OXY]-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-2-(TRIMETHYLSTANNYL)-, METHYL ESTER, 1,1-DIMETHYLETHYL CARBONATE 3,4-Dimethoxy-L-phenylalanine N-BENZOYL-2-HYDROXY-4,5-DIMETHOXYPHENYLALANINE ETHYL ESTER (S)-2-TERT-BUTOXYCARBONYLAMINO-3-(2,3,4-TRIMETHOXY-PHENYL)-PROPIONIC ACID D-Phenylalanine

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