BORTEZOMIB-PINANEDIOL

BORTEZOMIB-PINANEDIOL Basic information
Product Name:BORTEZOMIB-PINANEDIOL
Synonyms:BORTEZOMIB-PINANEDIOL;Bortezomib pinanediol ester;N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide;Bortezomib intermediates III;(1S,2S,3R,5S)-Pinanediol N-(2-pyrazinecarbony1)-L-phenylalanine-L-leucine boronate;Bortezomib impurity 4/Bortezomib Pinanediol Impurity/(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate;BortezoMib InterMediate III (BortezoMib pinanediol ester);BortezoMib VI
CAS:205393-22-2
MF:C29H39BN4O4
MW:518.46
EINECS:1806241-263-5
Product Categories:Boron Derivatives;Chiral Reagents;Intermediates
Mol File:205393-22-2.mol
BORTEZOMIB-PINANEDIOL Structure
BORTEZOMIB-PINANEDIOL Chemical Properties
Melting point 75-83°C
Boiling point 719.5±60.0 °C(Predicted)
density 1.19
storage temp. -20°C Freezer
solubility Chloroform, DMSO (Slightly), Ethanol, Ethyl Acetate, Methanol (Slightly)
form Solid
pka11.97±0.46(Predicted)
color Pale Yellow to Yellow
Safety Information
MSDS Information
BORTEZOMIB-PINANEDIOL Usage And Synthesis
Chemical PropertiesYellow Solid
UsesIntermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate proteasome inhibitor.
BORTEZOMIB-PINANEDIOL Preparation Products And Raw materials
Bortezomib Impurity 60 Bortezomib Impurity 47 HCl (S)-(+)-PINANEDIOL (DICHLORMETHYL)BORONATE Polycarbonate diol Bortezomib Impurity 32 (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide (IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt Desisobutyl-n-butyl BortezoMib Bortezomib Impurity 9 Bortezomib Impurity 52 POLY(CAPROLACTONE) DIOL, AVERAGE M.N. 2000 POLY(1 6-HEXAMETHYLENE ADIPATE) AVERAG& 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib intermediates II (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate cis-Pinane Bortezomib

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