humantenirine

humantenirine Basic information
Product Name:humantenirine
Synonyms:humantenirine;4-Demethyl-11-methoxyhumantenine;Spiro[3H-indole-3,8'(7'H)-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one, 3'-ethylidene-1',2',3',4',4'a,5',9',9'a-octahydro-1,6-dimethoxy-, (3S,3'Z,4'R,4'aS,7'R,9'aS)-;Humanlenirine
CAS:82375-30-2
MF:C21H26N2O4
MW:370.44
EINECS:
Product Categories:
Mol File:82375-30-2.mol
humantenirine Structure
humantenirine Chemical Properties
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
Safety Information
MSDS Information
humantenirine Usage And Synthesis
DescriptionHumantenirine is an oxindole alkaloid that has been shown to have potent inhibition of the enzyme activities. It is a natural product that has been isolated from the plant Humantenia nitens, which is found in Gabon, Africa. Humantenirine has a skeleton similar to other indole alkaloids and contains a hydroxy group on one of the rings. This compound has been shown to be stereoselective and monoterpenoid and may have potential as an anti-inflammatory drug.
Chemical PropertiesHumantenirine ( C21H26N2O4 colorless cubic crystals, mp 168- 169°C, M+ 370.1944). Its UV spectrum is similar to that of gelsemicine; hence both have the same chromophore, 7-methoxy-3,3-disubstituted N-methoxy-oxindole.
OccurrenceHumantenirine is a natural product found in Gelsemium sempervirens, Gelsemium elegans, and Gelsemium rankinii with data available.
targetP450 (e.g. CYP17)
humantenirine Preparation Products And Raw materials
Daurinoline HuMantenidine Xanthiazone veratramine rankinidine VERATRIDINE humantenmine koumine Xanthiside humantenine PICROSIDE I [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(E)-3-(4-hydroxy-3-methoxyphenyl)propenoyloxy]-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside L-Hyoscyamine daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one VERATRINE menisdaurin GELSEMICINE

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