|
| Product Name: | BUTEIN | | Synonyms: | (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one
2',3,4,4'-Tetrahydroxychalcone;BUTEIN(P);2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-;Butein
2',3,4,4'-Tetrahydroxychalcone;2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol;2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol;2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol;2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol | | CAS: | 487-52-5 | | MF: | C15H12O5 | | MW: | 272.25 | | EINECS: | 207-659-5 | | Product Categories: | Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 487-52-5.mol |  |
| | BUTEIN Chemical Properties |
| Melting point | 216°C | | Boiling point | 560.9±50.0 °C(Predicted) | | density | 1.483±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >50 mg/mL | | pka | 7.44±0.35(Predicted) | | form | solid | | color | yellow | | LogP | 2.405 (est) | | CAS DataBase Reference | 487-52-5(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 29145090 |
| | BUTEIN Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent | | Definition | ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. | | General Description | Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium). | | Biochem/physiol Actions | Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells. |
| | BUTEIN Preparation Products And Raw materials |
|
