|
| | 4-methylquinoline Basic information |
| | 4-methylquinoline Chemical Properties |
| Melting point | 9-10 °C(lit.) | | Boiling point | 261-263 °C(lit.) | | density | 1.083 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.620(lit.) | | Fp | >230 °F | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 5.67(at 20℃) | | form | Liquid | | color | Pale Orange | | Odor | at 100.00 %. burnt oily herbal floral sweet | | Odor Type | burnt | | Water Solubility | Slightly soluble | | Sensitive | Light Sensitive | | Merck | 14,5441 | | BRN | 110926 | | InChIKey | MUDSDYNRBDKLGK-UHFFFAOYSA-N | | LogP | 2.610 | | CAS DataBase Reference | 491-35-0(CAS DataBase Reference) | | NIST Chemistry Reference | Quinoline, 4-methyl-(491-35-0) | | EPA Substance Registry System | Quinoline, 4-methyl- (491-35-0) |
| | 4-methylquinoline Usage And Synthesis |
| Description | Refer to 6-METHYLQUINOLINE. | | Chemical Properties | clear slightly yellow to brown liquid | | Uses | Lepidine is used in the preparation of certain dyes. | | Uses | 4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging. | | Definition | ChEBI: A methylquinoline carrying a methyl substituent at position 4. | | Synthesis Reference(s) | Tetrahedron Letters, 28, p. 5291, 1987 DOI: 10.1016/S0040-4039(00)96710-8 | | General Description | Synthesis of lepidine from 4-anilinobutan-2-one in ethanol in the presence of HCl or FeCl3 has been reported. Nitration of lepidine has been reported. | | Purification Methods | Reflux lepidine with BaO, then fractionally distil it. Further purify it via its recrystallised dichromate salt (m 138o) (from H2O). [Cumper et al. J Chem Soc 1176 1962.] [Beilstein 20 III/IV 3477, 20/7 V 389.] |
| | 4-methylquinoline Preparation Products And Raw materials |
|
