ChemicalBook Product Catalog Biochemical Engineering Nucleoside drugs Nucleoside Intermediates 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Basic information
Product Name:4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)
Synonyms:2-amino-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one;2-amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;2-amino-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one;4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI);2-AMINO-3,5-DIHYDRO-PYRROLO[3,2-D]PYRIMIDIN-4-ONE;4H-Pyrrolo3,2-dpyrimidin-4-one, 2-amino-1,5-dihydro-;9-deazaguanine;2-amino-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
CAS:65996-58-9
MF:C6H6N4O
MW:150.14
EINECS:
Product Categories:Heterocycles;Nucleotides;PYRIMIDINE;AMINEPRIMARY;Heterocyclic Compounds;Bases & Related Reagents
Mol File:65996-58-9.mol
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Structure
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Chemical Properties
Melting point >300 °C(Solv: water (7732-18-5))
density 1.87±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka10.85±0.20(Predicted)
color Beige
Safety Information
MSDS Information
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Usage And Synthesis
Description9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.
Chemical PropertiesBeige Solid
UsesA nucleoside analog as potent inhibitor of purine nucleoside phosphorylase.
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Preparation Products And Raw materials
Preparation Products7-DEAZAGUANOSINE
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro- (9CI) 6H-Pyrrolo[3,2-d]pyrimidin-6-one, 4-amino-5,7-dihydro- (9CI) 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-amino-1,5-dihydro- (9CI) 9-deaza-9-(3-thienylmethyl)guanine Peldesine 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-7-DEAZA-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 2H-Pyrrolo[2,3-d]pyrimidin-2-one, 4-amino-1,7-dihydro- (9CI) 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 9-DEAZA-2'-DEOXYGUANOSINE (2-AMINO-7-(BETA-D-2-DEOXYRIBOFURANOSYL)PYRROLO[3,2-D]PYRIMIDIN-4-ONE) CI 972
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