5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Basic information

Product Name:	5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID
Synonyms:	5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID;5-Amino-2-chloropyridine-4-carboxylic acid ,97%;3-amino-6-chloroisonicotinicacid;5-Amino-2-chloro-4-pyridinecarboxylic acid;5-Amino-2-chloropyridine-4-carboxylic acid, 5-Amino-4-carboxy-2-chloropyridine;5-Amino-2-Chloroisonicotinic Acid(WXC01548);5-Amino-2-chloroisonicotinic;4-Pyridinecarboxylic acid, 5-amino-2-chloro-
CAS:	58483-95-7
MF:	C6H5ClN2O2
MW:	172.57
EINECS:	687-937-4
Product Categories:	Heterocycle-Pyridine series;Pyridine;Carboxylic Acids;Pyridines;Carboxylic Acids
Mol File:	58483-95-7.mol

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Chemical Properties

Boiling point	514.4±50.0 °C(Predicted)
density	1.577±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	3.74±0.10(Predicted)

Safety Information

Risk Statements	36/37/38
Safety Statements	22-26-36/37/39
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Usage And Synthesis

Chemical Properties	Brown powder
Uses	3-Amino-6-chloroisonicotinic Acid is a useful synthetic intermediate. It can be used to prepare inhibitors of the EGFr and c-erbB-2. It can also be used to synthesise modulators of GHSr-1a for the treatment of type II diabetes and obesity.

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Diethyl ether-->Dichloromethane-->Triethylamine-->Ammonium hydroxide-->n-Butyllithium-->Hexane-->1,4-Dioxane-->Di-tert-butyl dicarbonate-->CARBON DIOXIDE-->Trifluoroacetic acid-->N,N,N',N'-Tetramethylethylenediamine-->5-Amino-2-chloropyridine-->5-[(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROISONICOTINIC ACID-->5-[N-(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROPYRIDINE-->2-Amino-5-chloropyridine-->6-Chloronicotinic acid

6-[(4-bromophenyl)amino]-5-chloropyridine-3-carboxylic acid 6-[butyl(ethyl)amino]-5-chloropyridine-3-carboxylic acid 6-[(4-bromo-3-methylphenyl)amino]-3-chloropyridine-2-carboxylic acid 6-[bis(prop-2-en-1-yl)amino]-5-chloropyridine-3-carboxylic acid 6-[benzyl(ethyl)amino]-3-chloropyridine-2-carboxylic acid RARECHEM AL BW 1166 6-[(4-bromo-2-fluorophenyl)amino]-3-chloropyridine-2-carboxylic acid 6-[benzyl(methyl)amino]-3-chloropyridine-2-carboxylic acid ETHYL 2-CHLORO-3-CYANO-6-METHYL-5-NITROPYRIDINE-4-CARBOXYLATE 6-[(1-{bicyclo[2.2.1]heptan-2-yl}ethyl)amino]-3-chloropyridine-2-carboxylic acid 6-[(4-bromo-2-fluorophenyl)amino]-5-chloropyridine-3-carboxylic acid 6-amino-3-chloropyridine-2-carboxylic acid 6-[(2-bromo-4-fluorophenyl)amino]-3-chloropyridine-2-carboxylic acid 6-[butyl(ethyl)amino]-3-chloropyridine-2-carboxylic acid 5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID 6-[bis(prop-2-en-1-yl)amino]-3-chloropyridine-2-carboxylic acid 6-({2-[bis(propan-2-yl)amino]ethyl}amino)-5-chloropyridine-3-carboxylic acid 6-[(2-bromophenyl)amino]-3-chloropyridine-2-carboxylic acid

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