ChemicalBook Product Catalog API Hormones and the Endocrine System Pancreatic hormone and blood sugar regulation 1-butylbiguanide

1-butylbiguanide

1-butylbiguanide Basic information
Product Name:1-butylbiguanide
Synonyms:Butylbiguanide;Butyldiguanide;Dibetos B;Glybigid;H 224;N1-Butylbiguanide;N-BUTYLBIGUANIDINE;Buformin (base and/or unspecified salts)
CAS:692-13-7
MF:C6H15N5
MW:157.2168
EINECS:2117264
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:692-13-7.mol
1-butylbiguanide Structure
1-butylbiguanide Chemical Properties
Melting point 174-176 °C
Boiling point 271.89°C (rough estimate)
density 1.0291 (rough estimate)
refractive index 1.8070 (estimate)
pka12.27±0.10(Predicted)
Safety Information
MSDS Information
1-butylbiguanide Usage And Synthesis
UsesBuformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase
DefinitionChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.
Brand nameAdebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.
World Health Organization (WHO)Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)
1-butylbiguanide Preparation Products And Raw materials
Raw materialsBUTYLAMINE HYDROCHLORIDE-->Butylamine
N-((p-Chlorophenyl)amidino)-1-piperidinecarboxamidine hydrochloride chlorhexidine phosphanilate BuforMin Hydrochloride Chlorhexidine Diacetate CHLORHEXIDINE-RING-UL-14C DIGLUCONATE Chlorhexidine SPECS AG-690/12767754 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2(1H)-ONE HYDRAZONE Etoformin BPC 151 CHLORHEXIDINE-RING-UL-14C DIHYDROCHLORIDE 1-butylbiguanide N-((p-Chlorophenyl)amidino)-4-methyl-1-piperidinecarboxamidine monohyd rochloride Chlorhexidine hydrochloride Chlorhexidine diacetate ALEXIDINE DIHYDROCHLORIDE Poly(hexamethylenebiguanide) Chlorhexidine digluconate
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