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| | 6-Aminoquinoline Basic information |
| | 6-Aminoquinoline Chemical Properties |
| Melting point | 115-119 °C (lit.) | | Boiling point | 146 °C/0.3 mmHg (lit.) | | density | 1.1148 (estimate) | | refractive index | 1.7080 (estimate) | | Fp | 146°C/0.3mm | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform, DMSO, Methanol | | form | Solid | | pka | pK1: 5.63(+1) (20°C,μ=0.01) | | color | Pale Brown to Brown | | Water Solubility | Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water. | | Sensitive | Air Sensitive | | BRN | 113320 | | CAS DataBase Reference | 580-15-4(CAS DataBase Reference) | | NIST Chemistry Reference | 6-Quinolinamine(580-15-4) |
| | 6-Aminoquinoline Usage And Synthesis |
| Chemical Properties | Dark yellow to brown crystalline powder | | Uses | 6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. | | Uses | 6-Aminoquinoline was used as an internal standard in determining serum nicotine and cotinine simultaneously by using high-performance liquid chromatography (HPLC)-fluorometric detection with a postcolumn ultraviolet-photoirradiation system. It was also used as a fluorescent derivatizing agent for the detection of biochemicals and in the synthesis of tertiary N-methylated enaminonesa. | | Purification Methods | It is purified by column chromatography on a SiO2 column using CHCl3/MeOH (4:1) as eluent. It crystallises from *C6H6 or *C6H6/pet ether and is an irritant. The styphnate has m 239-240o (from EtOH) and m 242-243o (from aqueous Me2CO). [Barrett et al. J Chem Soc 50, 57 1953, Beilstein 22 III/IV 4681, 22/10 V 303.] |
| | 6-Aminoquinoline Preparation Products And Raw materials |
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