Fmoc-4-nitro-L-phenylalanine

Fmoc-4-nitro-L-phenylalanine Basic information

Product Name:	Fmoc-4-nitro-L-phenylalanine
Synonyms:	Fmoc-Phe(4-NO₂)-OH;9-FLUORENYLMETHOXYCARBONYL-P-NITRO-L-PHENYLALANINE;4-Nitro-L-phenylalanine, N-FMOC protected;Fmoc-L-4-NO2-Phe-OH;NALPHA-9-Fluorenylmethoxycarbonyl-3-(4-nitrophenyl)-L-alanine;N-(9-Fluorenylmethyloxycarbonyl)-L-4-nitrophenylalanine;FMOC-4-NITRO PHENYLALANINE;FMOC-4-NITRO-PHE-OH
CAS:	95753-55-2
MF:	C24H20N2O6
MW:	432.43
EINECS:
Product Categories:	Phenylalanine [Phe, F];Unusual Amino Acids;Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Fmoc-Amino acid series
Mol File:	95753-55-2.mol

Fmoc-4-nitro-L-phenylalanine Chemical Properties

Melting point	213-223℃
Boiling point	692.3±55.0 °C(Predicted)
density	1.371±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	almost transparency in N,N-DMF
pka	3.59±0.10(Predicted)
form	powder to crystal
color	White to Light yellow
BRN	5178656
CAS DataBase Reference	95753-55-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Safety Statements	22-24/25
WGK Germany	3
HS Code	2924 29 70
HazardClass	IRRITANT

MSDS Information

Provider	Language
SigmaAldrich	English

Fmoc-4-nitro-L-phenylalanine Usage And Synthesis

Chemical Properties	White powder
Uses	Fmoc-Phe(4-NO2)-OH is used to prepare squaric acid derivatives as VLA-4 integrin antagonists. It is also an intermediate used in the synthesis of analogs of kahalalide F.

Fmoc-4-nitro-L-phenylalanine Preparation Products And Raw materials

Raw materials	4-Nitro-3-phenyl-L-alanine-->N-(9-Fluorenylmethoxycarbonyloxy)succinimide-->9-Fluorenylmethyl chloroformate-->L-Phenylalanine
Preparation Products	(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(dimethylamino)phenyl)propanoic acid

4-Nitro-L-phenylalanine monohydrate Phenprobamate NITROGEN DIOXIDE L-Phenylalanine FMOC-L-PHE(3-F, 4-NO2) Fmoc-Aib-OH P-AMINO-DL-PHENYLALANINE FMOC-PHE-OH 9-Fluorenylmethyl chloroformate 4-Nitro-3-phenyl-L-alanine Fmoc-Phe-OH Fmoc-4-nitro-L-phenylalanine 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-(4-NITRO-PHENYL)-PROPIONIC ACID 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID 9-Fluorenemethanol FMOC-L-2,4-DINITROPHE D-Phenylalanine Fmoc-p(NH-Boc)-L-Phe-OH

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