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| | THIOBENZAMIDE Basic information |
| | THIOBENZAMIDE Chemical Properties |
| Melting point | 113-117 °C (lit.) | | Boiling point | 180 °C | | density | 1.1364 (rough estimate) | | refractive index | 1.5500 (estimate) | | Fp | 120°C | | storage temp. | Sealed in dry,Room Temperature | | form | Crystalline Powder | | pka | 12.68±0.29(Predicted) | | color | yellow | | Water Solubility | Slightly soluble in water. | | BRN | 606021 | | CAS DataBase Reference | 2227-79-4(CAS DataBase Reference) | | EPA Substance Registry System | Benzenecarbothioamide (2227-79-4) |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45-24/25 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | CV5860000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29309090 | | Toxicity | mnt-mus-orl 180 mmol/kg MUREAV 192,141,87 |
| | THIOBENZAMIDE Usage And Synthesis |
| Chemical Properties | Yellowish-green crystalline powder | | Uses | Thiobenzamide was used to prepare amide and amidine adducts. It was also used in the synthesis of 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides. | | Uses | Thiobenzamide is useful for the preparation of amide and amidine adducts. It is also used to prepare 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides. Further, it acts as a raw material in organic synthesis. | | Definition | ChEBI: Thiobenzamide is a member of benzenes. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 41, p. 962, 1976 DOI: 10.1021/jo00868a013
Synthesis, p. 917, 1978 DOI: 10.1055/s-1978-24939 | | Safety Profile | Poison by ingestion. Moderatelytoxic by intraperitoneal route. Questionable carcinogenwith experimental tumorigenic data. Mutation datareported. When heated to decomposition it emits verytoxic fumes of NOx and SOx. |
| | THIOBENZAMIDE Preparation Products And Raw materials |
| Raw materials | Benzenecarbothioamide, N-(4-methylphenyl)--->1,3,2-Dioxaphosphorinane, 5,5-dimethyl-2-[(phenylthioxomethyl)thio]-, 2-sulfide (9CI)-->Phenyl-3H-1,2,4-dithiazol-3-one | | Preparation Products | 4-(MORPHOLIN-4-YLMETHYL)-1,3-THIAZOL-2-AMINE-->2-PHENYL-1,3-THIAZOLE-4-CARBALDEHYDE-->2-PHENYL-1,3-THIAZOLE-4-CARBONYL CHLORIDE-->2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE-->2,4-DIPHENYL-1,3-THIAZOLE-5-CARBALDEHYDE-->(2-PHENYL-1,3-THIAZOL-4-YL)METHANOL-->4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBONYL CHLORIDE-->4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLIC ACID-->2-MORPHOLIN-4-YL-1,3-THIAZOL-4(5H)-ONE-->RARECHEM AL BI 1318-->FENTIAZAC-->ETHYL 4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE-->2,4-DIPHENYLTHIAZOLE-->Pre-IBS-->(2-PHENYL-THIAZOL-4-YL)-ACETIC ACID-->3-METHYL-THIOBENZAMIDE |
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