FMOC-Arg(Pbf)-OH

FMOC-Arg(Pbf)-OH Basic information
Product Name:FMOC-Arg(Pbf)-OH
Synonyms:na-fmoc-ng-(2,2,4,6,7-pentamethyl-*dihydrobenzofu;-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid;FMOC-N-OMEGA-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE;FMOC-NG-PBF-L-ARGININE;FMOC-ARG(PBF);FMOC-ARGININE(PBF)-OH;FMOC-ARG(PBF)-OH;FMOC-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE
CAS:154445-77-9
MF:C34H40N4O7S
MW:648.77
EINECS:604-954-4
Product Categories:Arginine [Arg, R];Fmoc-Amino Acids and Derivatives;Amino Acids;Fmoc-Amino acid series
Mol File:154445-77-9.mol
FMOC-Arg(Pbf)-OH Structure
FMOC-Arg(Pbf)-OH Chemical Properties
Melting point 132°C
alpha -5.5 º (c=1,DMF)
density 1.37±0.1 g/cm3(Predicted)
storage temp. Store at -15°C to -25°C.
solubility DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka3.83±0.21(Predicted)
color White to Off-White
optical activity[α]/D -5.5±1.0°, c = 1 in DMF
BRN 8302671
InChIKeyYUMOVWGGELTYES-LJAQVGFWSA-N
SMILESC(O)(=O)[C@H](CCCNC=NNS(C1=C(C)C(C)=C2OC(C)(C)CC2=C1C)(=O)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference154445-77-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 1
HS Code 2935 90 90
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-Arg(Pbf)-OH Usage And Synthesis
Chemical Propertieswhite powde
UsesFmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.
UsesFmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides. The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).
FMOC-Arg(Pbf)-OH Preparation Products And Raw materials
N-alpha-FMOC-Nepsilon-BOC-L-Lysine Nalpha-Fmoc-Ndelta-trityl-L-glutamine FMOC-ASU-OH N-Boc-N'-nitro-L-arginine Fmoc-Asp(OtBu)-OH FMOC-THR(TBU)-OL L-Fmoc-Aspartic acid alpha-tert-butyl ester ARGINASE Sulfuryl chloride 9-Fluorenylmethyl chloroformate FMOC-ARG(ME,PBF)-OH Fmoc-Phe-OH FMOC-Arg(Pbf)-OH arginine aspirin Fmoc L(+)-Arginine FMOC-b-Ala-OH N-(9-Fluorenylmethoxycarbonyloxy)succinimide

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