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| | trans-Chalcone Basic information |
| Product Name: | trans-Chalcone | | Synonyms: | PHENYL STYRYL KETONE;(2E)-1,3-DIPHENYLPROP-2-EN-1-ONE;2-BENZALACETOPHENONE;2-BENZYLIDENEACETOPHENONE;3-PHENYLACRYLOPHENONE;TRANS-BENZYLIDENEACETOPHENONE;TRANS-CHALCONE;1,3-DIPHENYL-2-PROPEN-1-ONE | | CAS: | 614-47-1 | | MF: | C15H12O | | MW: | 208.26 | | EINECS: | 210-383-8 | | Product Categories: | | | Mol File: | 614-47-1.mol |  |
| | trans-Chalcone Chemical Properties |
| Melting point | 55-59 °C | | Boiling point | 208 °C25 mm Hg(lit.) | | density | 1.0712 | | refractive index | 1.5361 (estimate) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly) | | form | Solid | | color | Pale Yellow | | Odor | at 100.00 %. floral balsam herbal | | Odor Type | floral | | Water Solubility | Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water. | | Merck | 14,2037 | | BRN | 509985 | | LogP | 4.013 (est) | | CAS DataBase Reference | 614-47-1(CAS DataBase Reference) | | NIST Chemistry Reference | Benzalacetophenone(614-47-1) |
| | trans-Chalcone Usage And Synthesis |
| Description | trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer. | | Uses | trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity. | | Definition | ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones. | | Application | trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O). | | Preparation | trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones | | Synthesis Reference(s) | Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058 | | General Description | trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer. | | Biological Activity | trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots. | | Biochem/physiol Actions | trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots. |
| | trans-Chalcone Preparation Products And Raw materials |
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