ChemicalBook Product Catalog Chemical Reagents Organic reagents Epoxide (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE

(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE

(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE Basic information
Product Name:(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
Synonyms:(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE;(2r)-(-)-(2,3-epoxy-2-methylpropylester)-4-nitrobenzoate;3-methyl-,4-nitrobenzoate,(r)-oxiranemethano;2,3-EPOXY-2-METHYLPROPYLESTER-4-NITROBENZOATE;2-methylglycidyl 4-nitrobenzoate;(R)-(2-Methyloxiran-2-yl)methyl 4-nitrobenzoate;(2R)-(-)-2-Methylglycidyl 4-nitrobenzoate ,98%;2-Oxiranemethanol, 2-methyl-, 2-(4-nitrobenzoate), (2R)-
CAS:106268-96-6
MF:C11H11NO5
MW:237.21
EINECS:
Product Categories:Chiral Building Blocks;Epoxides;Organic Building Blocks
Mol File:106268-96-6.mol
(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE Structure
(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE Chemical Properties
Melting point 87-89 °C(lit.)
Boiling point 379.74°C (rough estimate)
density 1.3350 (rough estimate)
refractive index 1.5300 (estimate)
storage temp. 2-8°C
solubility soluble in Chloroform, DCM
form Solid
color Light Yellow
optical activity[α]19/D 5.9°, c = 2.4 in chloroform
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
RTECS RR0510300
MSDS Information
ProviderLanguage
SigmaAldrich English
(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE Usage And Synthesis
Uses(R)-(-)-2-Methylglycidyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE Preparation Products And Raw materials
1-METHOXY-2-METHYL-2-PROPANOL GLYCIDYL METHYL ETHER (S)-(-)-Propylene oxide 2-Benzyloxyethanol (S)-(+)-1-BENZYLOXY-2-PROPANOL (S)-Oxiranemethanol (2R)-(-)-GLYCIDYL 4-NITROBENZOATE 2,3-epoxypropyl benzoate Methyl 4-nitrobenzoate Methyl 4-aminobenzoate 4-(METHOXYMETHYL)ANILINE Ethyl p-nitrobenzoate 4-AMINOBENZOIC ACID ISOBUTYL ESTER PROPYL 4-NITROBENZOATE BENZYL GLYCIDYL ETHER (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE 2-Methyl-2,3-epoxy-1-propanol (R)-(-)-1-BENZYLOXY-2-PROPANOL
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