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| | Diethyl chloromalonate Basic information |
| | Diethyl chloromalonate Chemical Properties |
| Boiling point | 279.11°C (rough estimate) | | density | 1.204 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.432(lit.) | | Fp | >230 °F | | storage temp. | Inert atmosphere,2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 9.07±0.46(Predicted) | | form | Liquid | | color | Clear colorless | | Specific Gravity | 1.204 | | LogP | 2.23 at 40℃ and pH4-9 | | CAS DataBase Reference | 14064-10-9(CAS DataBase Reference) | | EPA Substance Registry System | Propanedioic acid, 2-chloro-, 1,3-diethyl ester (14064-10-9) |
| Hazard Codes | C | | Risk Statements | 34-36/37 | | Safety Statements | 26-27-28-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29171990 |
| | Diethyl chloromalonate Usage And Synthesis |
| Chemical Properties | Clear Colourless Liquid | | Uses | Diethyl chloromalonate is a compound used in the models of aquatic toxicity developed
| | Uses | A compound used in the models of aquatic toxicity developed (QSAR). Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. | | General Description | Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K2CO3-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs2CO3 in the presence of elemental S8 or Sen to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes. |
| | Diethyl chloromalonate Preparation Products And Raw materials |
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