9-AMINOACRIDINE

9-AMINOACRIDINE Basic information
Product Name:9-AMINOACRIDINE
Synonyms:9-acridinamine;9-amino-acridin;9-Aminoakridin;Acridin-9-amine;Acridine, 9-amino-;Aminacrin;Aminoacridine;Izoacridina
CAS:90-45-9
MF:C13H10N2
MW:194.23
EINECS:201-995-6
Product Categories:Amines;Aromatics;Heterocycles
Mol File:90-45-9.mol
9-AMINOACRIDINE Structure
9-AMINOACRIDINE Chemical Properties
Melting point 238-240℃
Boiling point 320.68°C (rough estimate)
density 1.268
refractive index 1.5014 (estimate)
storage temp. Store below +30°C.
solubility ethanol: hazy
pka9.99(at 20℃)
form Solid
color Yellow
Water Solubility 11.65mg/L(24 ºC)
λmax406nm(DMF)(lit.)
Merck 14,407
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyXJGFWWJLMVZSIG-UHFFFAOYSA-N
CAS DataBase Reference90-45-9(CAS DataBase Reference)
EPA Substance Registry System9-Aminoacridine (90-45-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 2811
WGK Germany 3
RTECS AR7300000
HS Code 2933 99 80
HazardClass 6.1(b)
PackingGroup III
ToxicityLD50 intraperitoneal in mouse: 68mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
9-AMINOACRIDINE Usage And Synthesis
Chemical Propertiesyellow crystals or powder
UsesAcridine analog. DNA intercalating agent.
Usesantibacterial
UsesA MALDI matrix exhibiting low background and good sensitivity in the analysis of low molecular weight anions, such as metabolites, in negative mode
DefinitionChEBI: An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections
Brand nameMonacrin (Sterling Winthrop).
General DescriptionYellow needles. Free soluble in alcohol.
Air & Water ReactionsInsoluble in water.
Reactivity Profile9-AMINOACRIDINE is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.
Fire HazardFlash point data for 9-AMINOACRIDINE are not available; however, 9-AMINOACRIDINE is probably combustible.
Purification MethodsIt crystallises from EtOH or acetone and sublimes at 170-180o/0.04mm [Albert & Ritchie Org Synth Coll Vol III 53 1955, for hydrochloride, see below]. [Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.]
9-AMINOACRIDINE Preparation Products And Raw materials
Raw materialsPhosphorus pentachloride-->Anthranilic acid-->9-Chloroacridine
Preparation ProductsKallikrein
AURORA 17723 SALOR-INT L138673-1EA Amsacrine QUINACRINE MUSTARD DIHYDROCHLORIDE 2-ETHOXY-6,9-DIAMINOACRIDINE 6-CHLORO-9-[3-N-(2-CHLOROETHYL)ETHYLAMINO]PROPYLAMINO-2-METHOXYACRIDINE DIHYDROCHLORIDE Mepacrine hydrochloride 9-AMINOACRIDINE HCL,9-AMINOACRIDINE HYDROCHLORIDE 9-HYDRAZINOACRIDINE 9-Aminoacridine hydrochloride hydrate 6-CHLORO-9-[3-(2-CHLOROETHYLAMINO)PROPYLAMINO]-2-METHOXYACRIDINE DIHYDROCHLORIDE 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE NAM 9-AMINOACRIDINE AURORA 18755 Ethacridine lactate monohydrate 9-ACETAMIDOACRIDINE acrisorcin

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