Tripropyl orthoformate

Tripropyl orthoformate Basic information
Product Name:Tripropyl orthoformate
Synonyms:1,1′,1′′-[Methylidyntris(oxy)]trispropan;ORTHOFORMIC ACID TRI-N-PROPYL ESTER;ORTHOFORMIC ACID TRIPROPYL ESTER;ORTHOFORMIC TRIPROPYL ESTER;TRI-N-PROPYL ORTHOFORMATE;TRIPROPYL ORTHOFORMATE;TNPOF;Tripropyl orthoformate,98%
CAS:621-76-1
MF:C10H22O3
MW:190.28
EINECS:210-704-1
Product Categories:Acetals/Ketals/Ortho Esters;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Orthoesters;Acetals/Ketals/Ortho Esters;Organic Building Blocks;Oxygen Compounds
Mol File:621-76-1.mol
Tripropyl orthoformate Structure
Tripropyl orthoformate Chemical Properties
Boiling point 106-108 °C/40 mmHg (lit.)
density 0.883 g/mL at 25 °C (lit.)
refractive index n20/D 1.407(lit.)
Fp 162 °F
form Liquid
Specific Gravity0.883
color Clear colorless
Sensitive Moisture Sensitive
BRN 1744249
CAS DataBase Reference621-76-1(CAS DataBase Reference)
NIST Chemistry ReferenceTripropyl orthoformate(621-76-1)
EPA Substance Registry SystemTripropyl orthoformate (621-76-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39-37/39
RIDADR 1993
WGK Germany 1
10-21
TSCA Yes
HS Code 29159000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Tripropyl orthoformate Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesTripropoxymethane can be used in the lipase-?catalyzed esterification aimed at the kinetic resolution of racemic acids, circumventing the adverse effects of the water formed in the course of the reaction.
UsesTripropyl orthoformate was used as alcohol donor to investigate the activity and enantioselectivity of Novozym 435 in the esterification of rac-fenoprofen in methylcyclohexane. It may be used as a drying agent during the synthesis of squaraine derivatives.
Synthesis Reference(s)Journal of the American Chemical Society, 77, p. 3801, 1955 DOI: 10.1021/ja01619a036
General DescriptionGas phase reactions of the rare earth metal cations with tripropyl orthoformate were studied by Fourier transform ion cyclotron resonance mass spectrometry.
Tripropyl orthoformate Preparation Products And Raw materials
Preparation ProductsDIPROPYL SULFATE-->ACETALDEHYDE DIPROPYL ACETAL
Guaiacol carbonate Orthoformic acid triisobutyl ester 1,1,1-Trimethoxy-2-methylpropane MEZEREIN TRIDECYLORTHOFORMATE TETRA-N-PROPOXYMETHANE avilamycin A 2'-Hydroxy-3-phenylpropiophenone TRI(2-ETHYLHEXYL)ORTHOFORMATE ROPA THYMELEATOXIN Tri-n-amyl orthoformate, 98% TETRAKIS(2,2,3,3-TETRAFLUOROPROPYL)ORTHOCARBONATE BUTYL OLEATE TETRAKIS(2,2,3,3,4,4,5,5,6,6,7,7-DODECAFLUOROHEPTYL)ORTHOCARBONATE TRISTEARYL ORTHOFORMATE PROPYL FORMATE TRIISODECYL ORTHOFORMATE

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