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| | 1-Methyl-L-histidine Basic information |
| | 1-Methyl-L-histidine Chemical Properties |
| Melting point | ~240 °C (dec.) (lit.) | | alpha | -24 º (c=2% in H2O) | | Boiling point | 298.47°C (rough estimate) | | density | 1.2509 (rough estimate) | | refractive index | 1.5950 (estimate) | | storage temp. | 2-8°C(protect from light) | | solubility | Methanol (Slightly), Water (Slightly, Sonicated) | | form | Solid | | pka | 1.69(at 25℃) | | color | Off-White to Pale Beige | | optical activity | [α]20/D 24±1°, c = 2% in H2O | | BRN | 9727 | | Stability: | Hygroscopic | | CAS DataBase Reference | 332-80-9(CAS DataBase Reference) |
| | 1-Methyl-L-histidine Usage And Synthesis |
| Chemical Properties | Beige powder | | Uses | The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent developm
ent of cerivastatin-induced myotoxicity.
Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | | Uses | The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | | Definition | ChEBI: N(tele)-methyl-L-histidine is a L-histidine derivative in which the methyl group is at N(tele)-position. It has a role as a human metabolite. It is a L-histidine derivative and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a N(tele)-methyl-L-histidine zwitterion. |
| | 1-Methyl-L-histidine Preparation Products And Raw materials |
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