DL-TRIHEXYPHENIDYL HYDROCHLORIDE

DL-TRIHEXYPHENIDYL HYDROCHLORIDE Basic information
Product Name:DL-TRIHEXYPHENIDYL HYDROCHLORIDE
Synonyms:DL-Trihexyphenidyl.HCl;a-Cyclohexyl-a-phenyl-1-piperidinepropanol, HCl, Artane;Trihxexyphenidyl Hydrochloride;1-cyclohexyl-1-phenyl-3-piperidin-1-yl-propan-1-ol hydrochloride;1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol hydrochloride;1-cyclohexyl-1-phenyl-3-piperidino-propan-1-ol hydrochloride;α-Cyclohexyl-α-phenyl-1-piperidinepropanol, HCl, Artane;TRIHEXYPHENIDYL HCL
CAS:58947-95-8
MF:C20H32ClNO
MW:337.93
EINECS:627-735-5
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Antagonists;Cholinergics;Neurotransmitters
Mol File:58947-95-8.mol
DL-TRIHEXYPHENIDYL HYDROCHLORIDE Structure
DL-TRIHEXYPHENIDYL HYDROCHLORIDE Chemical Properties
Melting point 258.5°C dec.
storage temp. Refrigerator
solubility H2O: soluble
form solid
color white
Stability:Stable at RT
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
WGK Germany 3
RTECS TN2625000
MSDS Information
ProviderLanguage
SigmaAldrich English
DL-TRIHEXYPHENIDYL HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesCrystalline Solid
UsesDL-Trihexyphenidyl hydrochloride has been used to develop a capillary zone electrophoretic method with end-column electrochemiluminescence (ECL)-based detection technique.
UsesAntiparkinsonian;Anticholinergic
UsesDL-Trihexyphenidyl Hydrochloride is an anticholinergic tertiary amine that can gain access to the CNS. It is used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs. The drug is a muscarinic antagonist that qualitatively resembles the belladonna alkaloids in its pharmacological actions and side effects.
DefinitionChEBI: Trihexyphenidyl hydrochloride is an aralkylamine.
Biochem/physiol ActionsDL-trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is known to function as an antimuscarinic agent and a centrally acting anticholinergic. It can be used for controlling the symptoms of all Parkinsonism types, such as the idiopathic, and postencephalitic arteriosclerotic forms. Benzhexol hydrochloride exerts inhibitory functions on the parasympathetic nervous system.
DL-TRIHEXYPHENIDYL HYDROCHLORIDE Preparation Products And Raw materials
1-Piperidinepropanol DL-TRIHEXYPHENIDYL HYDROCHLORIDE

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