1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea

1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea Basic information
Product Name:1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea
Synonyms:Perflan;Perfmid;Preflan;Prefmid;sha105501;N-[5-[1,1-Dimethyl]-1,3,4-thiadiazol-2-yl]-N,N'-dimethylurea;1-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea/TEBUTHIURON;tebuthiuron (ISO) 1-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea
CAS:34014-18-1
MF:C9H16N4OS
MW:228.31
EINECS:251-793-7
Product Categories:Pesticides intermediate;Herbicides;TA - TEPesticides&Metabolites;Urea structure;Alpha sort;Pesticides&Metabolites;Alphabetic;Q-ZAlphabetic
Mol File:34014-18-1.mol
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea Structure
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea Chemical Properties
Melting point 161-164°C
density 1.2080 (rough estimate)
refractive index 1.6390 (estimate)
storage temp. 0-6°C
form Solid
pka13.36±0.46(Predicted)
color White to Light yellow
Water Solubility 2.3g/L(temperature not stated)
λmax255nm(lit.)
Merck 14,9095
BRN 527479
Exposure limitsLC50 (96-hour) for bluegill sun?sh 112 mg/L, rainbow trout 144 mg/L, gold?sh and fathead minnow >160 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats 644 mg/kg (Ashton and Monaco, 1991).
CAS DataBase Reference34014-18-1(CAS DataBase Reference)
NIST Chemistry ReferenceTebuthiuron(34014-18-1)
EPA Substance Registry SystemTebuthiuron (34014-18-1)
Safety Information
Hazard Codes Xn;N,N,Xn
Risk Statements 22-50/53
Safety Statements 37-60-61
RIDADR UN 3077
WGK Germany 3
RTECS YS4250000
HazardClass 9
PackingGroup III
HS Code 29349990
Hazardous Substances Data34014-18-1(Hazardous Substances Data)
ToxicityLD50 in mice, rats, rabbits (mg/kg): 579, 644, 286 orally (Todd)
MSDS Information
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea Usage And Synthesis
UsesTebuthiuron is an nonselective broad spectrum herbicide used to control weeds, woody and herbaceous plants.
UsesHerbicide.
UsesNonselective herbicide used to control herbaceous and woody plants on noncrop land.
DefinitionChEBI: Tebuthiuron is an organonitrogen heterocyclic compound and an organosulfur heterocyclic compound.
General DescriptionColorless odorless crystals. Non corrosive. Used as an herbicide.
Reactivity ProfileA urea, thiadiazole derivative.
Agricultural UsesHerbicide: Tebuthiuron is a broad-spectrum herbicide that is used to control weeds in non-cropland areas, range lands, rights-of-way and industrial sites. In grasslands and sugar cane it controls woody and herbaceous plants and weeds such as alfalfa, bluegrasses, chickweed, clover, dock, goldenrod and mullein. Not approved for use in EU countries[ 115]. Registered for use in the U.S.
Trade nameBRULAN®; BRUSH-BULLET®; E-103®; GRASLAN®; HERBEC®; HERBIC®; PERFLAN®; RECLAIM; SHA-105501®; SPIKE®; SPRAKIL®; TEBULAN®; TIUROLAN®
Environmental FateSoil. In microbially active soils, tebuthiuron is degraded via demethylation. The average half-life in soil 12–15 months in areas receiving 60 inches of rainfall a year (Humburg et al., 1989).
When tebuthiuron was applied to a rangeland at a rate of 0.84 kg/ha, 38% remained after 21 months (Emmerich et al., 1984).
Groundwater . According to the U.S. EPA (1986) tebuthiuron has a high potential to leach to groundwater .
Plant. Degrades in plants via N-demethylation and hydroxylation of the t-butyl sidechain (Hartley and Kidd, 1987; Humburg et al., 1989).


1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea Preparation Products And Raw materials
Raw materials2,2-Dimethylpropionic acid hydrazide-->Pivalic acid-->Methylamine-->1,3-Dimethylurea
DPX-T5648 Methylurea TEBUTHIURON SOLUTION 100UG/ML IN T-BUTYLMETHYL ETHER 1ML 2-Amino-5-methyl-1,3,4-thiadiazole 2-Amino-5-ethyl-1,3,4-thiadiazole TEBUTHIURON SOLUTION 100UG/ML IN T-BUTYLMETHYL ETHER 5X1ML TERT-BUTYL-1,3,4-THIADIAZOL-2-YL)-1,3-DIMETHYLUREA 5-isopropyl-1,3,4-thiadiazol-2-amine BUTHIDAZOLE 2-AMINO-5-TERT-BUTYL-1,3,4-THIADIAZOLE 2-Amino-1,3,4-thiadiazole 1,3-Dimethylurea 1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea TEBUTHIURON SOLUTION 100UG/ML IN T-BUTYLMETHYL ETHER 5ML BENZTHIAZURON TEBUTHIURON SOLUTION 100UG/ML IN ACETONITRILE 1ML

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