2,3-Dichloro-5-(trifluoromethyl)pyridine

2,3-Dichloro-5-(trifluoromethyl)pyridine Basic information

Product Name:	2,3-Dichloro-5-(trifluoromethyl)pyridine
Synonyms:	5,6-Dichloro-alpha,alpha,alpha-trifluoro-3-picoline;2,3- two-5- three fluorineMethyl pyridinechloride;2, 3 - dichloro - 5-3 Methyl pyridine;2,3-Dichloro-5-(trifluoromethyl)pyridine 97%;5-DCTF;BUTTPARK 45\10-37;2,3-DICHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;AKOS BBS-00006992
CAS:	69045-84-7
MF:	C6H2Cl2F3N
MW:	215.99
EINECS:	410-340-5
Product Categories:	Pyridine series;Chloropyridines;Halopyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Halides;Pyridines;Pyridine;Fluorine series;alkyl chloride;69045-84-7
Mol File:	69045-84-7.mol

2,3-Dichloro-5-(trifluoromethyl)pyridine Chemical Properties

Melting point	8-9 °C
Boiling point	80 °C20 mm Hg(lit.)
density	1.549 g/mL at 25 °C(lit.)
refractive index	n20/D 1.475(lit.)
Fp	175 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Chloroform, Methanol
pka	-3.34±0.10(Predicted)
form	Liquid
Specific Gravity	1.549
color	Clear colorless to yellow
CAS DataBase Reference	69045-84-7(CAS DataBase Reference)
EPA Substance Registry System	2,3-Dichloro-5-(trifluoromethyl)pyridine (69045-84-7)

Safety Information

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

2,3-Dichloro-5-(trifluoromethyl)pyridine Usage And Synthesis

Chemical Properties	Light yellow liquid
Uses	2,3-Dichloro-5-(trifluoromethyl)pyridine is a reactant that has been used in the synthesis of a 17b-HSD1 inhibitor.
General Description	2,3-Dichloro-5-(trifluoromethyl)pyridine is reported as an intermediate of herbicide. Synthesis of 2,3-dichloro-5-(trifluoromethyl)pyridine has been reported. Palladium-catalyzed monoalkoxycarbonylation of 2,3-dichloro-5-(trifluoromethyl)pyridine has been reported.

2,3-Dichloro-5-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials	Hydrogen fluoride-->2-Amino-5-methylpyridine-->2-Chloro-5-methylpyridine-->2-Chloro-5-trichloromethylpyridine-->2,3-Dichloro-5-(trichloromethyl)pyridine-->Propanal, 2,2-dichloro-3,3,3-trifluoro--->Antimony trifluoride-->2,6-Dichloromethyl pyridine hydrochloride-->TUNGSTEN(VI) CHLORIDE-->3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE-->Nickel-->3-Picoline-->Nicotinic acid-->Acrylonitrile
Preparation Products	3-CHLORO-2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE-->2,5,6-TRICHLORO-3-TRIFLUOROMETHYLPYRIDINE-->2,6-Dichloro-3-(trifluoromethyl)pyridine-->2-(3-chloro-5-(trifluoroMethyl)pyridin-2-yl)ethanaMine-->1-[3-CHLORO-5-(TRIFLUOROMETHYL)PYRID-2-YL]PIPERAZINE

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