Fmoc-Phe-OH

Fmoc-Phe-OH Basic information

Product Name:	Fmoc-Phe-OH
Synonyms:	FMOC-L-PHE;FMOC-L-PHENYLALANINE;FMOC-L-PHE-OH;(2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-phenylpropanoate;N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine ,98%;N-(9H-Fluorene-9-ylmethoxycarbonyl)phenylalanine;N-Fmoc-L-Phe-OH;Fmoc-Phenylalanine-OH
CAS:	35661-40-6
MF:	C24H21NO4
MW:	387.43
EINECS:	252-661-1
Product Categories:	A;Benzopyrans;Fluorenes, Flurenones;Amino Acids;Phenylalanine [Phe, F];Fmoc-Amino Acids and Derivatives;Protected Amino Acids;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series
Mol File:	35661-40-6.mol

Fmoc-Phe-OH Chemical Properties

Melting point	180-187 °C(lit.)
alpha	-38 º (c=1,DMF)
Boiling point	513.39°C (rough estimate)
density	1.2379 (rough estimate)
refractive index	-39.5 ° (C=1, DMF)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMF (Sparingly, Sonicated), DMSO (Slightly)
pka	3.77±0.10(Predicted)
form	Powder
color	White
optical activity	[α]20/D 37°, c = 1 in DMF
BRN	3597808
InChI	InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m0/s1
InChIKey	SJVFAHZPLIXNDH-QFIPXVFZSA-N
SMILES	C(O)(=O)[C@H](CC1=CC=CC=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference	35661-40-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-26
WGK Germany	3
HS Code	2924 29 70

MSDS Information

Provider	Language
FMOC-L-Phenylalanine	English
SigmaAldrich	English
ACROS	English
ALFA	English

Fmoc-Phe-OH Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	(Fmoc-Phe-OH) L-Phenylalanine (P319415) derivative, used in the preparation of peptides and deltorphin derivatives. A potential inhibitor of IGF-I and IGF-Binding Protein-5 complex.
General Description	The product number for this product was previously 04-12-1030. To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-Phe-OH Preparation Products And Raw materials

Raw materials	2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID-->Fmoc-D-phenylalanine-->L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2-propen-1-yl ester-->FMOC-PHE-OL-->methyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-phenylpropanoate-->L-Phenylalanine
Preparation Products	L-Phe-D-Trp-OH-->FMOC-PHE-PHE-OH-->ANGIOTENSIN I, HUMAN-->9H-Fluoren-9-ylmethyl(4S)-4-benzyl-5-oxo-1,3-oxazolidine-3-carboxylate-->ANGIOTENSIN I/II (4-8)

N-ALPHA-FMOC-L-PHENYLALANINE-METHYLAMIDE-SIEBER RESIN N-FMOC-L-PHENYLALANINE, [4-3H] FMOC-PHE-WANG RESIN FMOC-L-PHENYLALANINE N-HYDROXYSUCCINIMIDE ESTER,FMOC-L-PHENYLALANINE HYDROXYSUCCINIMIDE ESTER,FMOC-L-PHENYLALANINE HYDROXYSUCCINIMIDESTER FMOC-D-PHENYLALANINE extrapure,FMOC-D-Phenylalanine-OH,FMOC-D-PHENYLALANINE 99%,N-ALPHA-FMOC-D-PHENYLALANINE,N-FMOC-D-PHENYLALANINE,FMOC-D-PHENYLALANINE N-FMOC-L-PHENYLALANINE, [14C(U)] N-FMOC-L-PHENYLALANINE,N-ALPHA-FMOC-L-PHENYLALANINE,N-FMOC-PHE-OH,fmoc-phe-oh-2-13c Fmoc-Tyr(tBu)-OH Fmoc-L-phenylalanine 4-[poly(oxyethylene)carbamoyl]trityl ester polymer-bound N-FMOC-D-PHENYLALANINE, [1-14C] fmoc-L-phenylalanine N-carboxy anhydride N-ALPHA-FMOC-L-PHENYLALANINE (C1-13C),FMOC-PHE-OH (C1-13C) FMOC-D-PHENYLALANINE 4-BENZYLOXYBENZYL ESTER POLYMER BOUND Fmoc-Phe-OH-phenyl-d5-2,3,3-d3 FMOC-PHE-OH-15N,FMOC-L-PHENYLALANINE-15N FMOC-L-PHENYLALANINE-2-CHLOROTRITYL RESIN Fmoc-Phe-OH-13C9,15N Fmoc-(R)-3-Amino-3-phenylpropionic acid

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