2,2'-DITHIOBIS(5-NITROPYRIDINE)

2,2'-DITHIOBIS(5-NITROPYRIDINE) Basic information
Product Name:2,2'-DITHIOBIS(5-NITROPYRIDINE)
Synonyms:BIS(5-NITRO-2-PYRIDYL) DISULFIDE;2,2'-DITHIOBIS(5-NITROPYRIDINE);2,2’-dithiobis(5-nitro-pyridin;1,2-Bis(5-nitropyridin-2-yl)disulfane;Bis(5-nitro-2-pyridyl) disulfide, DTNP;5-nitro-2-(5-nitropyridin-2-yl)disulfanylpyridine;5-nitro-2-(5-nitropyridin-2-yl)disulfanyl-pyridine;5-nitro-2-[(5-nitro-2-pyridyl)disulfanyl]pyridine
CAS:2127-10-8
MF:C10H6N4O4S2
MW:310.31
EINECS:218-344-7
Product Categories:blocks;Pyridines
Mol File:2127-10-8.mol
2,2'-DITHIOBIS(5-NITROPYRIDINE) Structure
2,2'-DITHIOBIS(5-NITROPYRIDINE) Chemical Properties
Melting point 155-157 °C(lit.)
Boiling point 139°C (rough estimate)
density 1.6508 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Store at RT.
pka-2.88±0.29(Predicted)
form solid
color Brown
BRN 305413
CAS DataBase Reference2127-10-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 36/37/39
WGK Germany 3
RTECS UT2964000
HS Code 2933399990
MSDS Information
ProviderLanguage
SigmaAldrich English
2,2'-DITHIOBIS(5-NITROPYRIDINE) Usage And Synthesis
Uses2,2′-Dithiobis(5-nitropyridine) was employed:
  • as cysteine-activating reagent to study the NMR of G protein-coupled receptors
  • in the deprotection assays for protected selenocysteine-containing peptides
  • for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine
  • to remove the p-methoxybenzyl protecting group from cysteine and selenocysteine side-chains
General Description2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.
2,2'-DITHIOBIS(5-NITROPYRIDINE) Preparation Products And Raw materials
Preparation Products5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE
Pyridinethione 3-Nitropyridine 2-Pyridinethione 3-Aminopyridine 2,2'-Dithiodipyridine 2,2'-DITHIOBIS(5-NITROPYRIDINE) Dimethyl disulfide 2-MERCAPTO-5-NITROPYRIDINE 3-Amino-6-mercaptopyridine

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