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| | Quinaldic acid Basic information |
| | Quinaldic acid Chemical Properties |
| Melting point | 156-158 °C (lit.) | | Boiling point | 247-250 | | density | 1.2427 (rough estimate) | | refractive index | 1.5200 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | 14g/l | | form | Needle-Like Crystalline Powder | | pka | 1.20±0.30(Predicted) | | color | Light brown | | PH | 3.0-3.5 (10g/l, H2O, 20℃) | | Water Solubility | soluble | | Merck | 14,8046 | | BRN | 126322 | | CAS DataBase Reference | 93-10-7(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Quinolinecarboxylic acid(93-10-7) | | EPA Substance Registry System | 2-Quinolinecarboxylic acid (93-10-7) |
| | Quinaldic acid Usage And Synthesis |
| Chemical Properties | light brown needle-like crystalline powder | | Uses | For the determination of copper, zinc and uranium with which it forms insoluble salts. | | Uses | 2-?Quinolinecarboxylic acid can be found in the studying of ligands for the purpose of copper-catalyzed Ullmann reactions with aryl ethers and aryl iodides. | | Definition | ChEBI: A quinolinemonocarboxylic acid having the carboxy group at the 2-position. | | Synthesis Reference(s) | Journal of the American Chemical Society, 68, p. 1840, 1946 DOI: 10.1021/ja01213a045 | | General Description | Quinaldic acid is also referred as quinoline-2-carboxylic acid. Microwave-assisted preparation of substituted anilides of quinaldic acid has been reported. It inhibits the oxidation of pyruvate, α-ketoglutarate, glutamate and citrate in rat liver mitochondria. Quinaldic acid is a metabolite of tryptophan degradation and inhibits the gluconeogenesis in perfused livers. | | Purification Methods | Crystallise quinaldic acid from *C6H6 or AcOH. It is used for the estimation of many metals. The methyl ester has m 86-87o (from hexane) and pK25 1.76. [Chauduri et al. Frez Z Anal Chem 281 361 1976, Beilstein 22 H 71, 22 II 55, 22 III/IV 1149, 22/3 V 183.] |
| | Quinaldic acid Preparation Products And Raw materials |
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