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| | alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Basic information |
| | alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Chemical Properties |
| Melting point | 76°C | | Boiling point | 396.1±22.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Sparingly), Methanol (Sparingly) | | form | Solid | | pka | 14.50±0.20(Predicted) | | color | White to Light Yellow | | λmax | 319nm(H2O)(lit.) | | Merck | 14,8419 | | CAS DataBase Reference | 3366-95-8(CAS DataBase Reference) |
| | alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Uses | antiameobic, antitrichomonas | | Uses | Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas). | | Definition | ChEBI: Secnidazole is a C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 2-hydroxypropyl and methyl groups, respectively. It has a role as an epitope. It is a C-nitro compound, a member of imidazoles and a secondary alcohol. | | Pharmaceutical Applications | A 5-nitroimidazole with properties similar to those of metronidazole. It is rapidly absorbed after oral administration and is distinguished by having the longest plasma half-life (18 h) of clinically used nitroimidazole drugs. It is used in the treatment of intestinal amebiasis, giardiasis, trichomoniasis and bacterial vaginosis. |
| | alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Preparation Products And Raw materials |
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