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| | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Basic information | | Uses |
| Product Name: | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride | | Synonyms: | 6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1);6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride;5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride;6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1;Lifitegrast Intermediate 2;Lifitegrast Impurity 5;5,7-Dichloro-1,2,3,4-tetrahydro-6-isoquinolinecarboxylic acid hydrochloride (1:1);lifitegrast-impurity IV-3 | | CAS: | 1289646-93-0 | | MF: | C10H10Cl3NO2 | | MW: | 282.55 | | EINECS: | | | Product Categories: | | | Mol File: | 1289646-93-0.mol |  |
| | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Chemical Properties |
| InChI | InChI=1S/C10H9Cl2NO2.ClH/c11-7-3-5-4-13-2-1-6(5)9(12)8(7)10(14)15;/h3,13H,1-2,4H2,(H,14,15);1H | | InChIKey | CGXSFPJGZFRGNL-UHFFFAOYSA-N | | SMILES | ClC1C(=C(Cl)C=C2CNCCC=12)C(=O)O.Cl |
| | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Usage And Synthesis |
| Uses | 6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1) is a quinoline derivative used in pharmaceutical synthesis. | | General Description | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride, also known as Lifitegrast Impurity 5, is an impurity of Lifitegrast. Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. |
| | 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Preparation Products And Raw materials |
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