Oxamyl

Oxamyl Basic information
Product Name:Oxamyl
Synonyms:1-(dimethylcarbamoyl)-n-((methylcarbamoyl)oxy)thio-formidicacimethyles;2-(dimethylamino)-n-(((methylamino)carbonyl)oxy)-2-oxoethanimidothioicacidm;N-Methylcarbamic acid [(dimethylcarbamoyl)(methylthio)methylene]amino;N-Methylcarbamic acid [(dimethylcarbamoyl)(methylthio)methylene]amino ester;dpx1410;dpx1410l;Du pont 1410;dupont1410
CAS:23135-22-0
MF:C7H13N3O3S
MW:219.26
EINECS:245-445-3
Product Categories:OMore...Close...;Alpha sort;N-PPesticides&Metabolites;NematicidesAnalytical Standards;AcaricidesPesticides;Alphabetic;CarbamatesMethod Specific;Endocrine Disruptors (Draft)Pesticides&Metabolites;EPA;Insecticides;O;Pesticides;Pesticides&Metabolites
Mol File:23135-22-0.mol
Oxamyl Structure
Oxamyl Chemical Properties
Melting point 100°C
density 0.9700
vapor pressure 5.1×10-5Pa (25 °C)
refractive index 1.6630 (estimate)
storage temp. 0-6°C
solubility Chloroform: Slightly Soluble,Methanol: Slightly Soluble
pka10.48±0.46(Predicted)
form neat
Water Solubility 28 g/100 mL
BRN 2212753
Stability:Hygroscopic
CAS DataBase Reference23135-22-0(CAS DataBase Reference)
NIST Chemistry ReferenceOxamyl(23135-22-0)
EPA Substance Registry SystemOxamyl (23135-22-0)
Safety Information
Hazard Codes T+;N,N,T+
Risk Statements 21-26/28-51/53
Safety Statements 36/37-45-61
RIDADR UN 2811
WGK Germany 3
RTECS RP2300000
HazardClass 6.1(a)
PackingGroup I
Hazardous Substances Data23135-22-0(Hazardous Substances Data)
ToxicityLD50 orally in rats: 5 mg/kg (Fahmy)
MSDS Information
Oxamyl Usage And Synthesis
DescriptionOxamyl, is also called N,N-dimethyl-2-methylcarbamoyloxyimino- 2-(methylthio)acetamide (IUPAC), consists of colorless crystals, which are readily soluble in water, methanol, ethanol, acetone, and fairly soluble in toluene. Oxamyl is produced by chlorination of the oxime of methylglycolate, reaction with methanethiol and alkali, and conversion to the carbamate with methyl isocyanate.
UsesInsecticide, nematocide, acaricide.
UsesOxamyl is a broad spectrum systemic insecticide/nematicide. It exhibits both oral and contact toxicity to control both sucking and chewing insects and mites in a wide variety of row crops, fruits, vegetables and ornamentals.
UsesOxamyl is a pesticide used in the treatment and protection of crops from parasites and insects.
DefinitionChEBI: Oxamyl is a carbamate ester. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a carbamate insecticide, an acaricide, an antinematodal drug and an agrochemical. It is functionally related to a methylcarbamic acid.
Agricultural UsesInsecticide, Nematicide, Acaricide: A systemic and contact insecticide/acaricide and nematicide, oxamyl is a restricted use pesticide used on apples, bananas, carrots, celery, citrus, cotton, cucumbers, eggplants, garlic, ginger, muskmelon (including cantaloupe and honeydew melon), onion (dry bulb), peanuts, pears, peppers, peppermint, pineapples, plantains, potatoes, pumpkins, soybeans, spearmint, squash, sweet potatoes, tobacco, tomatoes, watermelons, yams. Oxamyl is also used on non-bearing apple, cherry, citrus, peach, pear, and tobacco. It is applied directly onto plants or the soilsurface. It is available in both liquid and granular form, but the granular form is banned in the U.S. It has no residential use. Registered for use in EU countries[115
Trade nameBLADE®; D-1410®; DPX 1410®; INSECTICIDE-NEMACIDE 1410®; OXAMYL CARBAMATE INSECTICIDE®; THIOXAMYL®; VYDATE®; VYDATE® 10G; VYDATE L®; VYDATE INSECTICIDE/NEMATICIDE®; VYDATE OXAMYL INSECTICIDE/NEMATOCIDE®[C]
Safety ProfilePoison by ingestion, skin contact, and inhalation. Experimental reproductive effects. Moderately toxic by skin contact. When heated to decomposition it emits very toxic fumes of NOx and SOx
Potential ExposureOxamyl is a white crystalline solid. Sulfur or garlic-like odor. Molecular weight=219.3
Environmental FateSoil. Oxamyl rapidly degraded in a loamy sand and fine sand soil at 25°C to carbon dioxide and the intermediate methyl N-hydroxy-N,N-dimethyl-1-thiooxaminidate (Rajagopol et al., 1984). The reported half-life in soil is approximately one week (Worthing and Hance, 1991). Ou and Rao (1986) reported a half-life in soil of 8–50 days. The reported half-lives of oxamyl in Pitstone, Devizes, Sutton Veany and Mepal soils at 15°C were reported to be 10.2–13.1, 6.2, 7.1 and 17.8 days, respectively (Bromilow et al., 1980). Smelt et al. (1987) reported that oxamyl degraded at a higher rate in field plots after repeated applications of this nematocide than in soils that received no treatment. The repeated applications of oxamyl to soils probably induced microbial activity, which resulted in the accelerated disappearance of this compound.
Harvey and Han (1978) reported a half-life of 8 days for oxamyl in soil.
Groundwater. According to the U.S. EPA (1986) oxamyl has a high potential to leach to groundwater.
Plant. Dislodgable residues of oxamyl on cotton leaf 0, 24, 48, 72 and 96 hours after application (0.41 kg/ha) were 1.5, 1.1, 1.2, 0.85 and 0.76 mg/m2, respectively (Buck et al., 1980).
Chemical/Physical. The hydrolysis half-lives of oxamyl in a sterile 1% ethanol/water solution at 25°C and pH values of 4.5, 6.0, 7.0 and 8.0, were 300, 17, 1.6 and 0.20 weeks, respectively (Chapman and Cole, 1982). Under alkaline conditions, oxam
Metabolic pathwayOxamyl degrades in soils, plants and animals following common metabolic pathways. Primary degradation reactions include the hydrolysis of the carbamate ester to yield the corresponding oxyimidothioate and nitrile. Other major metabolic reactions include N-demethylation and the hydration/oxidation of the nitriles to the corresponding amides and acids. The majority of the oxamyl metabolites are recovered as conjugates in plants and animals. No metabolites containing the oxidised thiomethyl group were observed. The primary degradation/metabolic pathways of oxamyl are presented in Scheme 1.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2991 Carbamate pesticides, liquid, toxic, flammable, flash point <23°C, Hazard Class: 6.1; Labels: 6.1-Poisonous material, 3-Flammable liquid.
DegradationOxamyl (1) was stable under acidic conditions but hydrolysed rapidly under basic conditions at 25 °C with DT50 values of >30 days at pH 5, 8 days at pH 7, and 3 hours at pH 9 (McNally and Wheeler, 1988). Cleavage of the methylcarbamoyl bond yielded methyl 2-( dimethylamino)- N-hydroxy-2-oxoethanimidothioate (2) as the primary hydrolysis product.
Exposure to artificial sunlight enhanced the degradation of oxamyl in pH 5 solution (DT50 7 vs. >30 days) to yield compound 2 (McNally, 1988). Rapid degradation of oxamyl was also observed in natural water exposed to natural sunlight (DT50 <1 day, Harvey and Han, 1978a). Compound 2 and its geometrical isomer (3) were major products observed in natural and distilled water exposed to artificial and natural sunlight. Further hydrolysis yielded (dimethy1amino)oxoacetica cid (4) as a minor photodegradation product in natural water exposed to natural sunlight.
IncompatibilitiesCompounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal 2264 Oxamyl practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Small quantities may be treated with alkali and buried in a landfill. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Oxamyl Preparation Products And Raw materials
Raw materialsOxiMino OxaMyl-->METHYLISOCYANATE 1 X 500MG NEAT
OXAMYL SOLUTION 100UG/ML IN ACETONITRILE 5X1ML Dacthal FORMOXIME Ethyl 2-(Chlorosulfonyl)acetate Ascoric Acid OXAMYL SOLUTION 100UG/ML IN ACETONITRILE 5ML OXAMYL SOLUTION 100UG/ML IN TOLUENE 1ML 4-Dimethylaminobenzoic acid CARBONYL SULFIDE WS-PT CARBAMATES & OXAMYL MIX ISOMETHIOZIN OxiMino OxaMyl Oxamyl OXAMYL SOLUTION 100UG/ML IN ACETONITRILE 1ML DPX Oxamyl emulsion(content<10%) OXAMYL D3 WS-PE CARBAMATES & OXAMYL MIX

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.