ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Serine derivatives H-SER(TBU)-OH

H-SER(TBU)-OH

H-SER(TBU)-OH Basic information
Product Name:H-SER(TBU)-OH
Synonyms:Ser(tBu);L-Ser(tBu)-OH;L-SERINE T-BUTYL ETHER;H-SER(BUT)-OH;H-SER(TBU)-OH;O-T-BUTYL-L-SERINE;O-TERT-BUTYL-L-SERINE;SERINE(TBU)-OH
CAS:18822-58-7
MF:C7H15NO3
MW:161.2
EINECS:606-131-5
Product Categories:Serine [Ser, S];Amino Acids and Derivatives;A - HPeptide Synthesis;Amino Acid Derivatives;Amino Acids;Peptide Synthesis;Amino Acids;Modified Amino Acids;Serine
Mol File:18822-58-7.mol
H-SER(TBU)-OH Structure
H-SER(TBU)-OH Chemical Properties
Melting point ~220 °C (dec.)
Boiling point 266.0±30.0 °C(Predicted)
density 1.080±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka2.11±0.10(Predicted)
form Powder
color White
Water Solubility Soluble in water.
CAS DataBase Reference18822-58-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29225090
MSDS Information
ProviderLanguage
SigmaAldrich English
H-SER(TBU)-OH Usage And Synthesis
Chemical PropertiesWhite powder
UsesO-tert-Butyl-L-serine tert-butyl ester hydrochloride is a protected L-serine used in peptide synthesis, e.g. synthesis of glycopeptides and lipopeptides and preparation of amino-phospholipids. O-tert-Butyl-L-serine (Ser(TBU-OH), a serine hydroxyl protected amino acid, is used in SPPS such as the synthesis of tailed cyclic RGD peptides to prevent glutarimide formation.
H-SER(TBU)-OH Preparation Products And Raw materials
Preparation ProductsFMOC-O-tert-Butyl-L-serine
H-SER(TBU)-OTBU HCL Z-SER(TBU)-OH,Cbz-Ser(tBu)-OH,Z-SER(TBU)-OH.DCHA,Z-L-SER(TBU)-OH FMOC-THR(TBU)-OPFP Z-THR(TBU)-OH DCHA FMOC-SER(TBU)-OPFP O,O'-di-tert-butyl-L-threonine acetate H-THR(TBU)-OTBU H-THR(TBU)-OME HCL Boc-Ser(tBu)-OH Fmoc-O-tert-Butyl-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester FMOC-L-SER(TBU)-OH,FMOC-SER(TBU)-OH,FMOC-O-TERT-BUTYL-L-SERINE (FMOC-L-SER(TBU)-OH) FMOC-O-tert-Butyl-L-threonine H-SER(TBU)-OME HCL H-SER(TBU)-OTBU H-THR(TBU)-OTBU HCL Z-Ser(tBu)-OH (dicyclohexylammonium) salt,Z-Ser(tBu)-OH dicyclohexylamine salt H-THR(TBU)-OH H-SER(TBU)-OH
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