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| | 20-HYDROXY PROSTAGLANDIN E2 Basic information |
| Product Name: | 20-HYDROXY PROSTAGLANDIN E2 | | Synonyms: | 20-HYDROXY PROSTAGLANDIN E2;(E)-7-[(1R,2S,3R)-2-[(E,3S)-3,8-dihydroxyoct-1-enyl]-3-hydroxy-5-oxo-cyclopentyl]hept-5-enoic acid;20-hydroxy-PGE2;20-hydroxy Prostaglandin E2 Lipid Maps MS Standard;AZIGEYVZEVXWAD-NZGURKHLSA-N;9-OXO-11ALPHA,15S,20-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 11,15,20-trihydroxy-9-oxo-, (5Z,11α,13E,15S)-;20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) | | CAS: | 57930-95-7 | | MF: | C20H32O6 | | MW: | 368.46 | | EINECS: | | | Product Categories: | | | Mol File: | 57930-95-7.mol |  |
| | 20-HYDROXY PROSTAGLANDIN E2 Chemical Properties |
| solubility | DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2) |
| | 20-HYDROXY PROSTAGLANDIN E2 Usage And Synthesis |
| Description | 20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 .1,2 ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent metabolic pathway for PGE2. 20-hydroxy PGE2 is the putative first intermediate in this chain of chemical transformations. | | Definition | ChEBI: 20-hydroxyprostaglandin E2 is a prostaglandin E derivative that is prostaglandin E2 in which one of the methyl hydrogens at position 20 has been replaced by a hydroxy group. It is a prostaglandins E, a secondary allylic alcohol, a primary alcohol and a triol. It is functionally related to a prostaglandin E2. It is a conjugate acid of a 20-hydroxyprostaglandin E2(1-). | | References | 1. Oliw, E.H. Observations on the substrate specificity of prostaglandin hydroxylases of monkey seminal vesicles and sheep vesicular glands Biochim. Biophys. Acta 1001,107-110(1989).
2. Oliw, E.H., Fahlstadius, P., and Hamberg, M. Isolation and biosynthesis of 20-hydroxyprostaglandins E1 and E2 in ram seminal fluid J. Biol. Chem. 261,9216-9221(1986). |
| | 20-HYDROXY PROSTAGLANDIN E2 Preparation Products And Raw materials |
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